Team:NTU-Singapore/Notebook/20 May 2008

From 2008.igem.org

Tuesday 20 May 2008

Finalising ideas

  • Bacteria detecting or emitting sound:
    • Gonna be a breakthrough if we succeed.
    • However, we cannot find any information about a particular bacterial gene, or at least a particular bacterium that can respond to sound.
  • Nguyen Xuan Hung: Simulation of fundamental biological interactions of ecosystem using bacteria.
    • We can start off with simple interactions between 2 species (predation,mutualism,competition...). From that, we can extend our system by building more complex tri-species interactions (sth like: the enemy of my enemy is my friend).
    • The constructs and modeling tasks seem doable.
    • Difficulty: hard to maintain sufficient environment for such system (as faced by Imperial College 06 team)
  • Bacteriocin:
    • Choon Kit: E-coli O157:H7 is among the most dangerous strains of E-coli. Remarkably, the use of antibiotic may provoke its virulence. Some types of bacteriocin can kill them.
    • Colicin E7 is the bacteriocin that can kill most of O157:H7 substrains.
We decide to choose this as our main project.