Team:Paris/Modeling/More f3 Algo

From 2008.igem.org

find_ƒ3 ( FliA )

function optimal_parameters = find_f3_FliA(X_data, Y_data, initial_parameters)
% gives the 'best parameters' involved in f3 with OmpR = 0 by least-square optimisation
% -> USE IT AFTER find_f3_OmpR
 
% X_data = vector of given values of ( [FliA]i ) (experimentally
% controled)
% Y_data = vector of experimentally measured values f3 corresponding of
% the X_data
% initial_parameters = values of the parameters proposed by the literature
%                       or simply guessed
%                    = [beta22, K6 -> (K6)/(coefOmp), n6]
 
global beta17; % parameter GIVEN BY find_f3_OmpR
 
     function output = act_pFlhDC(parameters, X_data)
         for k = 1:length(X_data)
                 output(k) = beta17*(1 - hill( X_data(k), parameters(2), parameters(3))) ...
                     + parameters(1)*hill(X_data(k), parameters(2), parameters(3));
         end
     end
 
options=optimset('LevenbergMarquardt','on','TolX',1e-10,'MaxFunEvals',1e10,'TolFun',1e-10,'MaxIter',1e4);
% options for the function lsqcurvefit
 
optimal_parameters = lsqcurvefit( @(parameters, X_data) act_pFlhDC(parameters, X_data), ...
     initial_parameters, X_data, Y_data, options );
% search for the fittest parameters, between 1/10 and 10 times the initial
% parameters
 
end

find_ƒ3 ( OmpR* )

function optimal_parameters = find_f3_OmpR(X_data, Y_data, initial_parameters)
% gives the 'best parameters' involved in f3 with FliA = 0 by least-square optimisation
% -> USE IT BEFORE find_f3_FliA
 
% X_data = vector of given values of ( [OmpR]i ) (experimentally
% controled)
% Y_data = vector of experimentally measured values f3 corresponding of
% the X_data
% initial_parameters = values of the parameters proposed by the literature
%                       or simply guessed
%                    = [beta17, K15 -> (K15)/(coefOmp), n15]
 
     function output = act_pFlhDC(parameters, X_data)
         for k = 1:length(X_data)
                 output(k) =(1 - hill( X_data(k), parameters(2), parameters(3) )) * parameters(1);
         end
     end
 
options=optimset('LevenbergMarquardt','on','TolX',1e-10,'MaxFunEvals',1e10,'TolFun',1e-10,'MaxIter',1e4);
% options for the function lsqcurvefit
 
optimal_parameters = lsqcurvefit( @(parameters, X_data) act_pFlhDC(parameters, X_data), ...
    initial_parameters, X_data, Y_data, options );
% search for the fittest parameters, between 1/10 and 10 times the initial
% parameters
 
end