University of Sheffield/18 July 2008

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Conclusion
As we intend to modify the E-Coli in a way so that its receptor can sense V.Cholera & Legionella. The problem here is both V.Cholera and Legionella have cascading pathways where reactions take place in a series of steps whereas in E.Coli all reactions are simultaneous. So we might have to introduce TWO plasmids in E.Coli to perform the job.