NYMU-Taipei/Project/Phosphate/Phosphate-related Medical Syndromes


 * When the phosphate level in blood exceeds 6.5 mg/dL, a patient kidney failure has a high risk of death
 * A high serum concentration of phosphate (pi) is clearly related to pruritus and hyperparathyroidism, both manifestations of the uremic syndrome
 * Phosphorus excess also inhibits 1 alpha-hydroxylase and hence the production of calcitriol, the active vitamin D metabolite
 * Phosphorus retention also alters polyamine metabolism by causing decreases in intestinal function and proliferation of intestinal villi