Team:TU Munchen/Projects

=Product Transport in E. Coli (E. Coli Filter)=


 * Goal: Make E. coli absorb some product.


 * Questions:
 * What products do we want E. coli to absorb?
 * How should E. coli absorb the products?


 * Notes:
 * Someone should research bioremediation to determine what products cause environmental problems.
 * We should understand transport across the cell envelope of Gram-negative bacteria.
 * E. coli do transport iron across their cell envelope. A great review is Close Before Opening.
 * A starting point for other metals is Structural Analysis and Classification of Native Proteins from E. Coli Commonly Co-Purified by Immobilised Metal Affinity Chromatography.


 * Bacteria used for extraction of gold "freeing": Called BIOX Process

=Chemotaxis Control (E. Coli Filter and E. Coli Rugby)=


 * Goal: Make E. coli follow/flee some chemical attractant/repellent.


 * Questions:
 * How does the chemotactic system work?


 * Notes:
 * Read Guiding Bacteria with Small Molecules and RNA.

=Mechanical Stress Detector=


 * Goal: Make E. coli respond to mechanical stress.


 * Questions:
 * How does mechanotransduction work in E. coli?


 * Notes:
 * Sound waves are mechanical stress, so this is an acoustic sensor. We would have to consider some frequency range.
 * Read Mechanotransduction: All Signals Point to Cytoskeleton, Matrix, and Integrins and Structure and Function of the Bacterial Mechanosensitive Channel of Large Conductance.

=Lipopolysaccharide Detector=


 * Goal: Make E. coli detect lipopolysaccharide (LPS).


 * Notes:
 * LPS leads to inflammation in higher organisms.

=Light Sensor (E. Coli Sunscreen)=


 * Goal: Make E. coli respond to varying intensities of light.