File:HD-Fig 2-colicinE1 structure.png

(a) Ribbon diagram of the Colicin E1 pore-forming domain by X ray crystal structure. The channel forming domain contains 10 helices (I-X). The two hydrophobic helices (VIII and IX) are labeled yellow. (b) Colicin E1 in a membrane bound state in two perspectives. Left panel shows the surface bound helices with an area of ~4200 Å2. Right panel shows colicin E1 bound to a lipid bilayer. The intra-membrane sections of the two helices VIII and IX are shown in yellow.