Here

From 2008.igem.org

(Difference between revisions)
Line 86: Line 86:
<br>
<br>
<img src="http://lh5.ggpht.com/coa07mhk/SQZQ0R3tEeI/AAAAAAAAAPA/N_x0O2WupfY/s800/G1.PNG" />
<img src="http://lh5.ggpht.com/coa07mhk/SQZQ0R3tEeI/AAAAAAAAAPA/N_x0O2WupfY/s800/G1.PNG" />
 +
<br>
 +
<br>
 +
The red curve is nearly half times wider than the green curve. It follows that standard deviation of red curve is greater thus the probability of contact (CAI-1 with Fusion kinase) is nearly half as compared to the probability of rest of reaction. To understand this consider an example of biscuits. Red curve shows each a biscuit made is different to the other produced under same conditions whereas green curve shows that the probability of two biscuits to be same is high.
<br>.
<br>.
</td>
</td>

Revision as of 23:15, 28 October 2008






Let us consider the probability of CAI-1 interacting with our fusion kinase with a reaction rate k, diffusion rates D1 and D2 and they start at a distance d apart at the beginning of the time intervalThe reaction between two diffusing particles can be considered to take place in two steps. First the encounter of CAI-1 with Fusion kinase and second the actual reaction of passing protein to response regulatory receptor. If we let CAI-1 as entity A and fusion kinase as entity B then the rate of reaction can given as:

Where
is the probability of interaction between CAI-1 and Fusion Kinase.
is the reaction once CAI-1 has interacted with Fusion Kinase.
This interaction will follow the law of diffusion and if we let the process under consideration as Poisson process, the probability can be given as:


To find the probability of rest of reaction i.e. from activation of UvrY till the shining of our protein we can use the Gaussian Distribution, which can be given as:




The red curve is nearly half times wider than the green curve. It follows that standard deviation of red curve is greater thus the probability of contact (CAI-1 with Fusion kinase) is nearly half as compared to the probability of rest of reaction. To understand this consider an example of biscuits. Red curve shows each a biscuit made is different to the other produced under same conditions whereas green curve shows that the probability of two biscuits to be same is high.
.

Retrieved from "http://2008.igem.org/Here"