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Team:Chiba/Project
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Project overview
E.coli time manager
- We control the timing of gene expression by using multiple signaling devices.To this end,we utilize molecules associated with Quorum sensing, a phenomenon that allows bacteria to communicate with each other.Our project uses two classes of bacteria: senders and receivers. Senders produce signaling molecules, and Receivers are activated only after a particular concentration of this molecule is reached.Although different quorum sensing species have slightly different signaling molecules, these molecules are not completely specific to their hosts and cross-species reactivity is observed.Communication using non-endogenous molecules is less sensitive, andrequires a higher signal concentration to take effect.This results in slower activation of receivers.
Project Design
About Quorum Sensing
Controlling the Delay time of the AHL signaling
- Quorum-Sensing Cross-talk
- LuxR/Plux mutant
Experiments
Results
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