Team:ETH Zurich/Project/Model Relevant

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[[Image:Gold_Algorithm.jpg|frame|none|Entire Algorithm]]
[[Image:Gold_Algorithm.jpg|frame|none|Entire Algorithm]]
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==== Modeling Framework ====
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This algorithm requires a modeling framework consisting of four main parts:
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# Statistical Analysis of DNA fragments produced by Restriction Enzymes
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# Flux Balance Analysis on a Genome Scale Model
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# Growth Simulations in Chemostat
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# Switch generator for short-time Restriction Enzyme Expressio
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Revision as of 17:06, 25 October 2008


Contents

Medal Relevant Issues

Silver Relevant

Gold Relevant

We propose a novel method of random gene deletion and chemostat-based selection of species with a reduced genome. For this we provide an algorithm described below.

Entire Algorithm

Modeling Framework

This algorithm requires a modeling framework consisting of four main parts:

  1. Statistical Analysis of DNA fragments produced by Restriction Enzymes
  2. Flux Balance Analysis on a Genome Scale Model
  3. Growth Simulations in Chemostat
  4. Switch generator for short-time Restriction Enzyme Expressio