Team:Illinois/Project

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Revision as of 02:17, 12 June 2008

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We are the inaugural iGEM team here at the University of Illinois. We are very excited to be participating and look forward to a summer full of fun, learning, and hopefully a successful project.

Overall project

For our project we intend to create a yeast-based biosensor capable of detecting and signalling the presense of a pathogen. We intend to use directed evolution to develop a cell surface receptor capable of binding the pathogen. This receptor will then initiate a signaling cascade which will induce a change in the yeast, a color change for example. This project is important because there is a demonstrated need for cheap and effective monitoring of water-borne pathogens in the third world where traditional detection methods are not feasible.

Subprojects

To improve our odds of achieving our project we have decided to modulate our team into 3 disparate groups, each pursuing variant methods to accomplish the above goal, that is, cheap detection of water-bourne pathogens. The three methods and teams are detailed below.

If you were not present at the June 10th meeting, pick a group and contact the members.

Antibody GPCR Fusion

Antibody Receptor Tyrosine Kinase Fusion

Bimolecular Fluorescence Biosensor

A soluble biosensor that activates a fluorescent protein upon binding a specific biomolecule.

Results

Home	The Team	Notebook	Research Articles	Protocols	The Project	Pictures	Parts Submitted to the Registry

@@ Line 37: / Line 37: @@
 === Bimolecular Fluorescence Biosensor ===
-A soluble biosensor that activates a fluorescent protein upon binding a specific biomolecule..
+A soluble biosensor that activates a fluorescent protein upon binding a specific biomolecule.
 == Results ==