Team:Imperial College

From 2008.igem.org

Revision as of 17:05, 24 October 2008 by Saint (Talk | contribs)


For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.




Pushed for time? For a basic overview of our project, you can look at the Summer Summary page.


An example of a useful application for our project is Biocouture. Visit our page on it to see what it's about!



Overview

The principle concepts of the Biofabricator subtilis project are:

  • First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
  • Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
  • Finally, when our bacteria are stationary in the correct location, the biomaterial production is triggered. These biomaterials can self-assemble to form a 3D bio-scaffold.


Please continue on to our project pages - you may want to start with our
>>> Project Specifications >>>





The Imperial College Team 2008 has received sponsorship from a number of generous companies. We are grateful for their kind support.



    < Previous