"
Team:MIT/Parts
From 2008.igem.org
(→Parts Submitted to the Registry) |
(→p1025) |
||
| Line 22: | Line 22: | ||
==== p1025 ==== | ==== p1025 ==== | ||
| - | This sequence codes for a short peptide, found to competitively inhibit binding of S.mutans to the tooth surface (Kelly CG et al.; Nature Biotechnol. 1999). S.mutans takes in sugars and secretes lactic acid, causing dental cavities, so introduction of this peptide into the mouth prevents colonies. | + | This sequence codes for a short peptide, found to competitively inhibit binding of S.mutans to the tooth surface ([http://www.ncbi.nlm.nih.gov/pubmed/9920267?dopt=Abstract|Kelly CG et al.; Nature Biotechnol. 1999]). S.mutans takes in sugars and secretes lactic acid, causing dental cavities, so introduction of this peptide into the mouth prevents colonies. |
This part uses the modified Silver BioBrick prefix and suffix to allow for protein construction. | This part uses the modified Silver BioBrick prefix and suffix to allow for protein construction. | ||
* BioBrick Number: | * BioBrick Number: | ||
Revision as of 15:04, 1 July 2008
| Home | The Team | The Project | Parts Submitted to the Registry | Modeling | Notebook |
|---|
Contents |
Parts Submitted to the Registry
GFP
Although there are multiple GFP parts in the registry already, this part uses the modified Silver BioBrick prefix and suffix to allow for protein construction.
- BioBrick Number:
- Sequence:
p1025
This sequence codes for a short peptide, found to competitively inhibit binding of S.mutans to the tooth surface (CG et al.; Nature Biotechnol. 1999). S.mutans takes in sugars and secretes lactic acid, causing dental cavities, so introduction of this peptide into the mouth prevents colonies. This part uses the modified Silver BioBrick prefix and suffix to allow for protein construction.
- BioBrick Number:
- Sequence:
L.bulgaricus signal
This is a short signal sequence recognized as a secretion tag by Lactobacillus strains. It was isolated at the 5' end of the prtB gene in Lactobacillus bulgaricus, which codes for a lactose digesting protein that is bound to the surface (Germond JE et al.; Appl Environ Microbiol. 2003).
| Home | The Team | The Project | Parts Submitted to the Registry | Modeling | Notebook |
|---|
