Team:NTU-Singapore

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*[http://www.ntu.edu.sg/scbe/cbe/FacultyPP/Profile_Matthew.htm Asst.Prof Matthew Chang]
*[http://www.ntu.edu.sg/scbe/cbe/FacultyPP/Profile_Matthew.htm Asst.Prof Matthew Chang]
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*Please kindly refer to our [https://2008.igem.org/wiki/index.php?title=Team:NTU-Singapore/Acknowledgements Acknowledgments] for the list of people we are grateful for their help they provided towards the success of our project.
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*• We would like to estend our special thanks to[http://www3.ntu.edu.sg/SCBE/cbe/FacultyPP/Profile_William.htm A/Prof William Chen] for his guidance and help rendered to the iGEM team. We would also like to thank Dr Tan Tuan Lin for guiding the team and providing valuable insights for the experiments.  
Email all: '''ntu.igem@gmail.com'''
Email all: '''ntu.igem@gmail.com'''

Revision as of 08:32, 2 July 2008


Contents

Team background

The NTU-Singapore iGEM08 team consists of six undergraduate students working full-time from May to July 2008 . In addition, we have a number of graduate students and faculty advisors.

Students


Faculty Advisors

  • [http://www.ntu.edu.sg/scbe/CBE/FacultyPP/Profile_ProfChing.htm Prof Ching Chi Bun]
  • [http://www.ntu.edu.sg/scbe/bioe/FacultyPP/Profile_CLPoh.htm Asst.Prof Poh Chueh Loo]
  • [http://www.ntu.edu.sg/scbe/cbe/FacultyPP/Profile_Matthew.htm Asst.Prof Matthew Chang]
  • • We would like to estend our special thanks to[http://www3.ntu.edu.sg/SCBE/cbe/FacultyPP/Profile_William.htm A/Prof William Chen] for his guidance and help rendered to the iGEM team. We would also like to thank Dr Tan Tuan Lin for guiding the team and providing valuable insights for the experiments.

Email all: ntu.igem@gmail.com

Our team logo

Project introduction

Our group has decided to engineer E.coli as a carrier for colicin E7 to deal with the pathogenic strain of Ecoli known as Escherichia coli O157:H7. Escherichia coli O157:H7 is an enterohemorrhagic strain that can cause bloody diarrhea and kidney failure. Current methods of cure for the infection include blood transfusion and dialysis. Currently no antibiotic is able to kill it.

Our approach is to use Colicin E7 to kill this harmful strain of bacteria. We intend to use our very own genetically engineered E.coli as the carrier of the colicin. We also wish for our bacteria to able to detect the presence of blood and the bacteria before it releases the colicins to eradicate the pathogen.

Our aim would be to control the level of colicin production in our bacteria. Our engineered bacteria should also be able to be accurate in its detection.


For any comments or enquiries, contact us at ntu.igem@gmail.com

Upcoming important event

1 July Team project descriptions due (Early summer teams)
Team registration fee due
1 September Final team rosters due
1 October Jamboree attendance fees due; notice and description of any use of non-standard parts or devices schemes due
15 October Project Summary forms due (to allow for organization of judging)
29 October Project and part documentation due
29 October BioBrick Part DNA received by the Registry
8-9 November iGEM Competition Jamboree, MIT, USA

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