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Team:Peru/Project
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== Project Details== | == Project Details== | ||
| + | Mechanical processes are involved in nearly every facet of the cell cycle. Mechanical forces are generated in the cell during processes as diverse as chromosomal segregation, replication, transcription, translation, translocation of proteins across membranes, cell locomotion, and catalyzed protein and nucleic acid folding and unfolding, among others. Our objetive is to understand the role of mechanical force in biochemistry. | ||
== References == | == References == | ||
Revision as of 17:48, 1 August 2008
| Home | The Team | The Project | Parts Submitted to the Registry | Modeling | Notebook |
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Overall project
Project Details
Mechanical processes are involved in nearly every facet of the cell cycle. Mechanical forces are generated in the cell during processes as diverse as chromosomal segregation, replication, transcription, translation, translocation of proteins across membranes, cell locomotion, and catalyzed protein and nucleic acid folding and unfolding, among others. Our objetive is to understand the role of mechanical force in biochemistry.
References
- Chemla, Y.R., Moffitt, J.R., and C. Bustamante, Exact Solutions for Kinetic Models of Macromolecular Dynamics. J. Phys. Chem. B 112(19), 6025 -6044 (2008)
- Bustamante C, Liphardt J, Ritort F. The nonequilibrium thermodynamics of small systems. Physics Today 58 (7): 43-48 JUL (2005).
- Bustamante C, Chemla YR, Forde NR & Izhaky D . Mechanical processes in biochemistry. Annual Review of Biochemistry (2004) 73: 705-748.
- Bustamante C, Bryant Z, Smith SB. Ten years of tension: single-molecule DNA mechanics. Nature (2003) 421: 423 - 427
