"
Team:Peru/Project
From 2008.igem.org
(→Project Details) |
(→Overall project) |
||
| Line 9: | Line 9: | ||
== '''Overall project''' == | == '''Overall project''' == | ||
| - | + | Mechanical forces are generated in the cell during processes as diverse as chromosomal segregation, replication, transcription, translation, translocation of proteins across membranes, cell locomotion, and catalyzed protein and nucleic acid folding and unfolding, among others as protein folding, DNA elasticity, the protein-induced bending of DNA and the nduced catalysis of enzymes. Our objetive is to understand the role of mechanical force in biochemistry. | |
== Project Details== | == Project Details== | ||
Revision as of 17:53, 1 August 2008
| Home | The Team | The Project | Parts Submitted to the Registry | Modeling | Notebook |
|---|
Contents |
Overall project
Mechanical forces are generated in the cell during processes as diverse as chromosomal segregation, replication, transcription, translation, translocation of proteins across membranes, cell locomotion, and catalyzed protein and nucleic acid folding and unfolding, among others as protein folding, DNA elasticity, the protein-induced bending of DNA and the nduced catalysis of enzymes. Our objetive is to understand the role of mechanical force in biochemistry.
Project Details
Mechanical forces are generated in the cell during processes as diverse as chromosomal segregation, replication, transcription, translation, translocation of proteins across membranes, cell locomotion, and catalyzed protein and nucleic acid folding and unfolding, among others as protein folding, DNA elasticity, the protein-induced bending of DNA and the nduced catalysis of enzymes. Our objetive is to understand the role of mechanical force in biochemistry.
References
- Chemla, Y.R., Moffitt, J.R., and C. Bustamante, Exact Solutions for Kinetic Models of Macromolecular Dynamics. J. Phys. Chem. B 112(19), 6025 -6044 (2008)
- Bustamante C, Liphardt J, Ritort F. The nonequilibrium thermodynamics of small systems. Physics Today 58 (7): 43-48 JUL (2005).
- Bustamante C, Chemla YR, Forde NR & Izhaky D . Mechanical processes in biochemistry. Annual Review of Biochemistry (2004) 73: 705-748.
- Bustamante C, Bryant Z, Smith SB. Ten years of tension: single-molecule DNA mechanics. Nature (2003) 421: 423 - 427
