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OFFICIAL RELEASE: Clotho Alpha!

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Overall project

Genomics has reached the stage at which the amount of DNA sequence information in existing databases is quite large. Synthetic biology now is using these databases to catalog sequences according to their functionality and therefore creating standard biological parts which can be used to create large systems.


As these databases grow, the need for integrated tools that perform complex operations, organize information, and automate regular processes is becoming increasingly obvious. The synthetic biology community could be better-served with the development of flexible tools which not only permit access and modification to that data but also allow one to perform meaningful manipulation and use of that information in an intelligent and efficient way. These tools need to be useful to biologists working in a laboratory environment while leveraging the experience of the larger CAD community.


This project develops a toolset called "Clotho" which provides a variety of design views and tools to aid biologists to modify existing synthetic biological systems as well as create new ones. These tools differ from current offerings in this area in that they not only provide the needed tools to manipulate designs in one complete system but also provide unique ways in which to visualize the design as well as a number of connections to both local and global part repositories.

Project Abstract

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Project Details

Overall Timeline

  • iGEM 1st Meeting: June 2, 2008 - Nade and Matt start.
  • Anne arrives:
  • Check-up with Prof. Anderson:
  • iGEM picture session:
  • Clotho Testing Session 1: July 14th, 2008
  • Clotho Testing Session 2: July 16th, 2008
  • Anne leaves (and sadness ensues): August 1st, 2008
  • Clotho Beta Release:
  • iGEM 2008 Jamboree:

Part 1: Getting Acquainted To Clotho

Part 2: The Testing Sessions

Information and pictures regarding the testing sessions can be found here.

Part 3: The Alpha Release

Part 4: The Path Forward

Clotho Development

Clotho development information can be found here.