Team:University of Sheffield

From 2008.igem.org

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!align="center"|[[Team:University_of_Sheffield /Wet Lab|Wet Lab]]
!align="center"|[[Team:University_of_Sheffield /Wet Lab|Wet Lab]]
!align="center"|[[Team:University_of_Sheffield /Lab Books| Our team]]
!align="center"|[[Team:University_of_Sheffield /Lab Books| Our team]]
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!align="center"|[[Team:University_of_Sheffield /Timetable| Timetable]]
!align="center"|[[Team:University_of_Sheffield /Misc| Miscellaneous]]
!align="center"|[[Team:University_of_Sheffield /Misc| Miscellaneous]]
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Revision as of 23:04, 27 October 2008

UniShefBanner.jpg


Introduction Our project Modelling Wet Lab Our team Timetable Miscellaneous


On a Mission for Fluorescence...

E.coli transformed with GFP plasmid.

Expression of non-native receptor proteins in bacteria often involves extensive genetic modifications that can be difficult to carry out. One way of addressing this problem involves creating a fusion receptor protein consisting of the sensing part from the foreign species and the signal transmitting part native to the organism in which receptor is to be expressed. The fusion receptor we have designed consists of Vibrio Cholerae's sensing module fused to E.coli's signal conveyer. The receiver part of the receptor should bind to signaling molecules excreted by V.cholera and pass it downstream through signal transmitter to DNA. The expression of a reporter molecule will indicate water contamination. As a result, the fusion receptor could be utilised as the basis for a cheap water contamination sensor. Read more.

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