Team:PennState

Penn State University has participated in the International Genetically Engineered Machines (iGEM) competition for four years as of 2008, and we are excited to participate once more. Our team consists of 5 undergraduate students, one visiting undergrad and one high school student who work independently, coordinated through weekly meetings with our advisers. Check out our Team Page to meet us!

Our main focus for 2008 was the elimination of diauxie in E. coli to create a xylose inducible system independent of glucose regulation. This system could be used for creating more efficient bioproduction by altering the utilization of 5 and 6 carbon sugars. Please check out the links on the left to navigate through our work.

Two other projects begun this year focus on creating biosensors that use human nuclear hormone receptors to recognize potentially harmful compounds. These receptor systems occur naturally in the human body, but our goal is to retain and utilize their functions in E. coli. The links on the left should introduce you to our thought process and progress on each of these projects, and provide a fuller introduction to the topic.

Please explore our website to find out more about us and our projects! If there are any questions or comments about the information on this site please feel free to contact us at gjt5001@psu.edu.

Medal Checklist

Drew Endy On Synthetic Biology

Garrett Tobin On Diauxie Elimination

Sponsors for our team! Thanks so much!

@@ Line 1: / Line 1: @@
 <html>
-<!--
-   Landing page
-   Contains links to all other pages of the site as well as a quick introduction to the projects
-   The aim of this page was to be visually appealing and contain a very small amount of text so that the user would be given a quick introduction to the project. The   user has only to read several lines to get a good grasp of what we did. This will encourage them to explore deeper.
--->
 <head>
-<!--
-   Cascading Style Sheet (CSS) component
-   in plain html style sheets are completely independent of the HTML page but are included in this page to simplify design within a wiki script environment.
-   This section describes the layout, colors and images displayed on the page
--->
 <style>
 #globalWrapper {
   background-image: url("https://static.igem.org/mediawiki/2008/e/e4/Bglogo.png") !important;
   background-repeat: repeat;
 }
@@ Line 125: / Line 115: @@
 #pagecontent p {
   text-indent: 1.25em;
+}
+p.start:first-line {
+ font-weight: bold;
+ letter-spacing: 1.2;
 }
 </style>
@@ Line 134: / Line 129: @@
 <!-- First table displays centered iGEM 2007 Logo -->
 <div id="header">
-  <img src="https://static.igem.org/mediawiki/2008/d/df/Penn_state_igem_logo.JPG" alt="Penn State" />
+  <img src="https://static.igem.org/mediawiki/2008/a/ad/Penn_state_igem_logo2.JPG" alt="Penn State" />
 </div>
@@ Line 156: / Line 151: @@
 -->
 <td valign="top" width="20%" id="projectnav">
-  <h4 style="margin-top: 0;">Hormone Biosensors</h4>
+  <h4>Diauxie Elimination</h4>
   <dl id="hbnav">
-   <dd><a href="hbintro" title="Intro to Endocrine Disruption, pseudoestrogens, pthalates, nuclear hormone receptors, and our goals">Introduction</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/intro">Introduction</a></dd>
-  <dt>Smart Fold</dt>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/TheSystem">The System</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/smartfold/overview">Overview</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/Strategies">Strategies</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/smartfold/parts" title="Parts submitted to the registry for this project">Parts</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/progress">Progress</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/smartfold/references">References</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/conclusions">Conclusions</a></dd>
-  <dt>Nuclear Fusion</dt>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/parts" title="Parts submitted to the registry for diauxie">Parts</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/fusion/overview">Overview</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/references">References</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/fusion/parts" title="Parts submitted to the registry for this project">Parts</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/fusion/references">References</a></dd>
   </dl>
-  <h4>Diauxie Elimination</h4>
+  <h4><acronym title="Nuclear Hormone Receptor">NHR Biosensors</acronym><br/></h4>
   <dl id="denav">
-   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/intro">Introduction</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/NHR/introduction">NHR Introduction</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/overview">Overview</a></dd>
-   <dd><a href="https://2008.igem.org/Team:PennState/diauxie/parts" title="Parts submitted to the registry for this project">Parts</a></dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/smartfold/overview">Phthalate Biosensor</a></dd>
-  <dd><a href="https://2008.igem.org/Team:PennState/diauxie/references">References</dd>
+   <dd><a href="https://2008.igem.org/Team:PennState/fusion/overview">BPA Biosensor</a></dd>
   </dl>
 </td>
 <!-- Main content area -->
-<td valign="top" id="pagecontent"><span style="font-size: 16pt">PENN STATE iGEM 2008</span>
+<td valign="top" id="pagecontent" width="80%"><span style="font-size: 16pt">Welcome to Penn State iGEM 2008</span>
   <hr />
-    <p>Welcome to the Penn State iGEM 2008 team’s website. We are currently working hard at a few different projects for this year's competition. Our main focus for 2008 was the elimination of diauxie in <em>E. coli</em> to create a xylose inducible system independent of glucose regulation. This system could be used for creating more efficient bioproduction by altering the utilization of 5 and 6 carbon sugars.</p>
+    <p class="start"><a href="http://www.psu.edu" title="Pennsylvania State University" target="_blank">Penn State University</a> has participated in the International Genetically Engineered Machines (iGEM) competition for four years as of 2008, and we are excited to participate once more. Our team consists of 5 undergraduate students, one visiting undergrad and one high school student who work independently, coordinated through weekly meetings with our advisers. Check out our <a href="https://2008.igem.org/Team:PennState/Team" title="Penn State's 2008 iGEM team">Team Page</a> to meet us!</p>
-    <p>We also have been working on creating biosensors that use human nuclear hormone receptors to recognize potentially harmful compounds. These receptor systems occur naturally in the human body, but our goal is to retain and utilize their functions in <em>E. coli</em>. Please explore our website to find out more about us and our projects!</p>
+ <p><strong>Our main focus for 2008 was the elimination of <a href="https://2008.igem.org/Team:PennState/diauxie/intro">diauxie</a> in <em>E. coli</em> to create a xylose inducible system independent of glucose regulation.</strong> This system could be used for creating more efficient bioproduction by altering the utilization of 5 and 6 carbon sugars. Please check out the links on the left to navigate through our work.</p>
-   <p> If there are any questions or comments about the information on this site please contact us at <a href="mailto:gjt5001@psu.edu" title="email us">gjt5001@psu.edu</a>. </p>
+    <p>Two other projects begun this year focus on creating <a href="https://2008.igem.org/Team:PennState/NHR/introduction"What kind of 'Biosensors' are we talking about?">biosensors</a> that use human nuclear hormone receptors to recognize potentially harmful compounds. These receptor systems occur naturally in the human body, but our goal is to retain and utilize their functions in <em>E. coli</em>. The links on the left should introduce you to our thought process and progress on each of these projects, and provide a fuller introduction to the topic.</p>
+   <p> Please explore our website to find out more about us and our projects! If there are any questions or comments about the information on this site please feel free to contact us at <a href="mailto:gjt5001@psu.edu" title="email us">gjt5001@psu.edu</a>. </p>
+    <span style="font-size: 14pt"><a href="https://2008.igem.org/Team:PennState/MedalChecklist">Medal Checklist</a></span>
+<table>
    <tr>
-    <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: 14pt">Quick Links</span>
+    <td style="padding-top:30px; padding-right:30px" valign="top" width="45%">
-            <hr />
+     <h3>Related Links</h3>
-            <br/>
+     <hr />
-            <p><a href="http://parts.mit.edu/igem07/index.php/PennState/final_result#contributions" title="Our Contribution To the Registry">Table of our Contributions to the Registry</a></p>
+     <ul>
-            <p><a href="http://parts.mit.edu/igem07/images/7/73/IgemDesign.swf" title="Interactive Schematic" target="_blank">Interactive <em>E. co</em>Lisa Schematic</a></p>
+       <li><a href="http://partsregistry.org/Main_Page" title="Parts Registry">Parts Registry</a></li>
-            <p> <a href="http://www.psu.edu" title="Pennsylvania State University" target="_blank">Pennsylvania State University</a> </p>
-            <p> <a href="http://www.environment.psu.edu/" title="Penn State Institutes of Energy and the Environment" target="_blank">Penn State Institutes of Energy and the Environment</a> </p>
+<li><a href="http://www.che.psu.edu/Faculty/Cirino/" title="Prof. Pat Cirino's Lab website" target="_blank">Prof. Pat Cirino's Lab website</a></li>
-    <p> <a href="http://www.cmtc.psu.edu/" title="Center for Molecular Toxicology and Carcinogenesis" target="_blank">Center for Molecular Toxicology and Carcinogenesis</a> </p>
+<li><a href="http://www.abe.psu.edu/fac/Richard/Overview.htm" title="Prof. Tom Richard's Lab website" target="_blank">Prof. Tom Richard's Lab website</a></li>
-            </div>
+<li><a href="http://openwetware.org/wiki/IGEM:PennState" title="Penn State iGEM OpenWetWare" target="_blank">Penn State iGEM OpenWetWare</a></li>
-          </td>
-          <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: 14pt">Drew Endy On Synthetic Biology</span>
-            <hr />
+       <li><a href="http://www.princeton.edu/che/people/faculty/wood/" title="David Wood" target="_blank">David Wood</a></li>
+       <li><a href="http://www.cmtc.psu.edu/" title="Center for Molecular Toxicology and Carcinogenesis" target="_blank">PennState Center for Molecular Toxicology and Carcinogenesis</a></li>
-			<!--
+     </ul>
-			    This division block contains the code to import and display a flash object
+   </td>
-				Specifically importing and formatting a video uploaded onto "youtube"
+   <td style="padding-top:30px; padding-right:30px" valign="top" width="45%">
-			-->
+     <h3>Drew Endy On Synthetic Biology</h3>
+       <hr />
+	<!--
+	   This division block contains the code to import and display a flash object
+	   Specifically importing and formatting a video uploaded onto "youtube"
+	-->
              <div style="margin:10px">
-              <object width="200">
-                <param name="movie" value="http://www.youtube.com/v/XIuh7KDRzLk&rel=1">
+<object width="205" height="200">
-                </param>
+<param name="movie" value="http://www.youtube.com/v/XIuh7KDRzLk&hl=en&fs=1"></param><param name="allowFullScreen" value="true">
-                <param name="wmode" value="transparent">
+</param>
-                </param>
+<embed src="http://www.youtube.com/v/XIuh7KDRzLk&hl=en&fs=1" type="application/x-shockwave-flash" allowfullscreen="true" width="205" height="200">
-                <embed src="http://www.youtube.com/v/XIuh7KDRzLk&rel=1" type="application/x-shockwave-flash" wmode="transparent" width="200" ></embed>
+</embed>
-              </object>
+</object>
-             </div></td>
+            </div>
-        </tr>
+    </td>
-      </table>
+<td style="padding-top:30px; padding-right:30px" valign="top" width="45%">
+     <h3>Garrett Tobin On Diauxie Elimination</h3>
+       <hr />
+	<!--
+	   This division block contains the code to import and display a flash object
+	   Specifically importing and formatting a video uploaded onto "youtube"
+	-->
+ <div style="margin:10px">
+    <object width="205" height="200">
+      <param name="movie" value="http://www.youtube.com/v/QA-tETsb3Wo&hl=en&fs=1">
+       </param>
+      <param name="allowFullScreen" value="true">
+       </param>
+      <embed src="http://www.youtube.com/v/QA-tETsb3Wo&hl=en&fs=1" type="application/x-shockwave-flash"  allowfullscreen="true" width="205" height="200">
+       </embed>
+     </object>
+             </div>
+    </td>
+ </tr>
+</table>
 </td></tr></table> <!-- end the table for content quadrants -->
 </td></tr></table> <!-- end content block that is adjacent to sidelinks -->