Latest revision as of 03:55, 30 October 2008

	Home	The Team	E. nigma Project	Parts Submitted to the Registry	Notebook

Davidson College - Missouri Western State University

iGEM 2008

E. nigma: XOR Gates, a Bacterial Hash Function, and Viz-A-Brick

Our team designed, modeled, and constructed a bacterial computer that uses XOR logic to compute a cryptographic hash function. Hash functions are used to authenticate the integrity of a document by computing its digital fingerprint. Our bacterial computers are designed to recognize the presence or absence of two chemical signals via intercellular communication. Mathematical modeling of these computers has shown that our hash functions are difficult to corrupt. We designed and built a number of new parts, and improved and gained experience on existing parts. We also produced a graphical interface for exploring the Registry of Standard Biological Parts called Viz-A-Brick, and other web-based tools to improve the construction of new parts with BioBrick ends.

Highlights For Judges

New Parts Contributed to the Registry - we designed, built, and contributed 105 new parts to the Registry

Experience gained on new Registry parts - we measured the function of several of the new parts we designed, and some expectations were met

Improvement of pre-existing Registry parts - we redesigned the lac promoter and the lac repressor and measured an improvement in their functions

Online tools that support design of new BioBrick parts - we created online tools to aid in part design.

Viz-A-Brick: A new way to visualize the registry - we created a new interface to the Registry that addresses Human Practice issues associatated with navigating the expanding Registry

E. nigma Project - we designed and constructed several systems for using logic gates to compute hash functions in bacteria

iGEM 2008 powerpoint presentation Media:MWSU_Davidson_iGEM08.PPT

iGEM 2008 poster Media:MWSU_Davidson_iGEM08_poster.PPT

Funding - This collaborative project has received major support from National Science Foundation Grants #DMS-0733952 & 0733955, and was also supported by HHMI grant # 52006292, Davidson College DRI, the Davidson College Martin Genomics Program, the Missouri Western Foundation and the Missouri Western Office of Academic and Student Affairs.

Home	The Team	E. nigma Project	Parts Submitted to the Registry	Notebook

@@ Line 1: / Line 1: @@
+{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
+![[Image:Spy1.jpg|30px]] <br>
+!align="center"|[[Team:Davidson-Missouri_Western|Home]]
+!align="center"|[[Team:Davidson-Missouri_Western/Team|The Team]]
+!align="center"|[[Team:Davidson-Missouri_Western/Project|''E. nigma'' Project]]
+!align="center"|[[Team:Davidson-Missouri_Western/New_Parts_Contributed_to_the_Registry|Parts Submitted to the Registry]]
+!align="center"|[[Team:Davidson-Missouri_Western/Notebook|Notebook]]
+|}
 <font size = "6"><center>
 Davidson College - Missouri Western State University
@@ Line 6: / Line 14: @@
 iGEM 2008
 </center></font>
+<center>
+[[Image:E_nigma_logo.jpg|400 px]] [[Image:vizabrick_logo.png|259 px]]
+<br>
+</center>
+''' ''E. nigma'': XOR Gates, a Bacterial Hash Function, and Viz-A-Brick'''
-[[Image:Chambers_TeamPic_070308.jpg|right|thumbnail|500px|The Davidson / Missouri Western synthetic biology team]][[Image:TeamiGEM2008Logo.jpg|389px]]
+Our team designed, modeled, and constructed a bacterial computer that uses XOR logic to compute a cryptographic hash function. Hash functions are used to authenticate the integrity of a document by computing its digital fingerprint.  Our bacterial computers are designed to recognize the presence or absence of two chemical signals via intercellular communication. Mathematical modeling of these computers has shown that our hash functions are difficult to corrupt. We designed and built a number of new parts, and improved and gained experience on existing parts.  We also produced a graphical interface for exploring the Registry of Standard Biological Parts called Viz-A-Brick, and other web-based tools to improve the construction of new parts with BioBrick ends.<br><br>
+<center>
-'''Team Description'''
+<span style="color:red">
+='''Highlights For Judges'''=
-This team is composed of faculty and undergraduates from Davidson College in Davidson, North Carolina USA and from Missouri Western State University in Saint Joseph, Missouri USA and includes one student from Spelman College and one student from Hampton University. This is the third year of this iGEM collaboration for the faculty members and the first year for each of the fifteen students. This year, the team worked collaboratively from the two campuses for most of the summer but spent one week visiting each other's campuses, working shoulder-to-shoulder. The above picture was taken in July on the steps of the Chambers Building on the Davidson College campus.
+</span>
+</center>
-'''Project Abstract'''
-E. nigma: XOR Gates, a Bacterial Hash Function, and Viz-A-Brick
-Our team designed, modeled, and constructed a bacterial computer that uses XOR logic to compute a cryptographic hash function. Hash functions are used to authenticate the integrity of a document by computing its digital fingerprint, an integer value that can be compared to the publicized value. Our bacterial computers are designed to recognize the presence or absence of two chemical signals via intercellular communication. Mathematical modeling of these computers has shown that our hash functions are difficult to corrupt. We designed and built a number of new parts, and improved and gained experience on existing parts.  We also produced a graphical interface for exploring the Registry of Standard Biological Parts called Viz-A-Brick, and other web-based tools to improve the construction of new parts with BioBrick ends.
-'''Highlights'''
 '''[[Team:Davidson-Missouri_Western/New Parts Contributed to the Registry|New Parts Contributed to the Registry]]''' - we designed, built, and contributed 105 new parts to the Registry
-'''[[Team:Davidson-Missouri_Western/Experience Gained on New Registry Parts|Experience gained on new registry parts]]''' - we measured the function of several of the new parts we designed, and some expectations were met
+'''[[Team:Davidson-Missouri_Western/Experience Gained on New Registry Parts|Experience gained on new Registry parts]]''' - we measured the function of several of the new parts we designed, and some expectations were met
-'''[[Team:Davidson-Missouri_Western/Improvement of Pre-existing Registry Parts|Improvement of pre-existing registry parts]]''' - we redesigned the lac promoter and the lac repressor and measured an improvement in their functions
+'''[[Team:Davidson-Missouri_Western/Improvement of Pre-existing Registry Parts|Improvement of pre-existing Registry parts]]''' - we redesigned the lac promoter and the lac repressor and measured an improvement in their functions
-'''[[Team:Davidson-Missouri_Western/Online tools that support the design of new biobrick parts]]''' - we created online tools to aid in part design
+'''[[Team:Davidson-Missouri_Western/Online Tools that Support Design of New Biobrick Parts|Online tools that support design of new BioBrick parts]]''' - we created online tools to aid in part design.
-'''[[Team:Davidson-Missouri_Western/Viz-A-Brick: A new way to visualize the Registry]]''' - we created a new interface to the Registry that addresses Human Practice issues associatated with navigating the expanding Registry
+'''[[Team:Davidson-Missouri_Western/Viz-A-Brick: A New Way to Visualize the Registry|Viz-A-Brick: A new way to visualize the registry]]''' - we created a new interface to the Registry that addresses Human Practice issues associatated with navigating the expanding Registry
-'''[[Team:Davidson-Missouri_Western/E. nigma Project]]''' - we designed and constructed several systems for using logic gates to compute hash functions in bacteria
+'''[[Team:Davidson-Missouri_Western/Project|''E. nigma'' Project]]''' - we designed and constructed several systems for using logic gates to compute hash functions in bacteria
 <br/>
-iGEM 2008 powerpoint presentation
+i'''GEM 2008 powerpoint presentation''' [[Media:MWSU_Davidson_iGEM08.PPT]]
-iGEM 2008 poster
-'''Objective: Create Ideal Hash Function that Bacteria will Compute'''
-[[Ideal Hash Function Characteristics]]
-[[Hash Functions and Biological Systems]]
-[[Our Models]]
+'''iGEM 2008 poster'''  [[Media:MWSU_Davidson_iGEM08_poster.PPT]]
-[[Analysis of Our Models]]
+'''Funding''' - This collaborative project has received major support from National Science Foundation Grants #DMS-0733952 & 0733955, and was also supported by HHMI grant # 52006292, Davidson College DRI, the Davidson College Martin Genomics Program, the Missouri Western Foundation and the Missouri Western Office of Academic and Student Affairs.
-[[Matlab Files]]
+<center>
+[[Image:Davidson_logo.JPG|140 px]]   &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;    [[Image:Nsflogo.jpg|59 px]]      [[Image:HHMI.gif]]      [[Image:Western_logo.JPG|140 px]]
+</center>
-[[Future Work]]
 <!--- The Mission, Experiments --->
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 !align="center"|[[Team:Davidson-Missouri_Western|Home]]
 !align="center"|[[Team:Davidson-Missouri_Western/Team|The Team]]
-!align="center"|[[Team:Davidson-Missouri_Western/Project|The Project]]
+!align="center"|[[Team:Davidson-Missouri_Western/Project|''E. nigma'' Project]]
-!align="center"|[[Team:Davidson-Missouri_Western/Parts|Parts Submitted to the Registry]]
+!align="center"|[[Team:Davidson-Missouri_Western/New_Parts_Contributed_to_the_Registry|Parts Submitted to the Registry]]
-!align="center"|[[Team:Davidson-Missouri_Western/Modeling|Modeling]]
 !align="center"|[[Team:Davidson-Missouri_Western/Notebook|Notebook]]
 |}
-(''Or you can choose different headings.  But you must have a team page, a project page, and a notebook page.'')

Team:Davidson-Missouri Western

From 2008.igem.org

Latest revision as of 03:55, 30 October 2008

Highlights For Judges