Team:EPF-Lausanne/Project
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The idea of the project is to build a cellular system that allows the cell to respond in different ways according to the received signal, emitted by the neighbouring cells. It will then emit its proper signal that will be transfered to the following cells. | The idea of the project is to build a cellular system that allows the cell to respond in different ways according to the received signal, emitted by the neighbouring cells. It will then emit its proper signal that will be transfered to the following cells. | ||
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+ | == Biomedical application == | ||
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+ | We may be able to aplly this idea to automated system of drug producing for personal medicine. In such a system, you just put a sample of blood in the furst column of a microfluidic chip, then engineered cells in the wells detect some solutes, antibodies, and so and produce a signal given what thex detect. Then the signal is integrated along the chip and the last column is filled with engineered cells able to produce a given drug to cure diseases detected in the first well. | ||
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+ | As you would certainly suppose, we will not be able to engineer all the cell types to aim this goal in one summer, but we want through our project to make a few first steps to make such a system feasable in the future. | ||
== Project Details== | == Project Details== |
Revision as of 08:05, 11 July 2008
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Contents |
Two-colors signalling system
Overall project
The idea of the project is to build a cellular system that allows the cell to respond in different ways according to the received signal, emitted by the neighbouring cells. It will then emit its proper signal that will be transfered to the following cells.
Biomedical application
We may be able to aplly this idea to automated system of drug producing for personal medicine. In such a system, you just put a sample of blood in the furst column of a microfluidic chip, then engineered cells in the wells detect some solutes, antibodies, and so and produce a signal given what thex detect. Then the signal is integrated along the chip and the last column is filled with engineered cells able to produce a given drug to cure diseases detected in the first well.
As you would certainly suppose, we will not be able to engineer all the cell types to aim this goal in one summer, but we want through our project to make a few first steps to make such a system feasable in the future.
Project Details
The idea of the project is to build a system which uses two different quorum sensing sets of molecules that make the cell able to integrate three different levels of signal, and emit a different response, by producing a given fluorescent protein and a quorum sensing molecule.