Team:Rensselaer/Project

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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2008.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, and a lab notebook.  PLEASE keep all of your pages within your Team:Example namespace. 
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|align="center"|[[Team:Rensselaer | Team Example 2]]
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== '''Overall project''' ==
== '''Overall project''' ==
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Our team's aim is to use specific compounds in media to induce color differentiation. Cells would respond to different compounds depending on the types of genes that are induced by these concentrations, which would trigger a release of pigments that depended on the type of compound that the cell would sense. A possibility is to induce cell migration depending on the location and concentration of these inducers in the media. A possible application of this is for use of biosensors to test water contamination, given a certain concentration of contaminants. Our project could also be adapted toward homeostasis and curing of metaboloic diseases.
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Our aim is to develop a novel, micro organism based, sensor using bioinformatics resources and molecular biology techniques. We will genetically modify E. Coli cells to produce various pigments in response to certain compounds in the immediate environment. In addition to simply detecting compounds, we propose to engineer a molecular machine sensitive enough to resolve and even quantify target compound concentrations. This can be achieved in two ways: (1) by measuring color intensity or (2) distinguishing color combinations. We believe that this design can be extrapolated to areas such as bioremediation or for the application of biosensors to test water contamination, given a certain concentration of contaminants. Our project could be further adapted towards the maintenance of homeostasis given metabolic disorders as well as the treatment of metabolic diseases by replacing pigment expression with pharmacological proteins.
== Project Details==
== Project Details==

Latest revision as of 23:09, 28 July 2008

Ls lgp 2c.gif
Home The Team The Project Parts Submitted to the Registry Modeling Notebook


Contents

Overall project

Our aim is to develop a novel, micro organism based, sensor using bioinformatics resources and molecular biology techniques. We will genetically modify E. Coli cells to produce various pigments in response to certain compounds in the immediate environment. In addition to simply detecting compounds, we propose to engineer a molecular machine sensitive enough to resolve and even quantify target compound concentrations. This can be achieved in two ways: (1) by measuring color intensity or (2) distinguishing color combinations. We believe that this design can be extrapolated to areas such as bioremediation or for the application of biosensors to test water contamination, given a certain concentration of contaminants. Our project could be further adapted towards the maintenance of homeostasis given metabolic disorders as well as the treatment of metabolic diseases by replacing pigment expression with pharmacological proteins.

Project Details

Part 2

The Experiments

Part 3

Results

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