Team:NYMU-Taipei

Approximately 1.3 million people globally have chronic kidney failure that requires either renal transplantation or dialysis - for such patients, the established treatment is hemodialysis
The mortality rate of patients undergoing maintenance hemodialysis remains unacceptably high.
An extremely high morbidity and a relatively low quality of life (due in part to a high level of dependence and unemployment) and high cost have also been observed.

Our Design:

After ingesting our BacToKidney capsule, it passes the through stomach without taking any action, nor being digested, and proceeds to the small intestine. Once in the small intestine, the pH Sensor detects the change in pH and activates the clearance processes of Urea, Phosphate, and Guanidine from the body. To allow itself more time to perform its tasks, the pH Sensor also activates the Attachment process, making the capsule attach itself to the small intestine. After a pre-selected amount of time has passed (controlled by the time regulating oscillators), the capsule detaches itself from the small intestine and exits the body.

The parts our project is made up of:

pH Sensor
- A sensor of proton concentration (pH)
Attachment
- An Attachment anchor that attaches to the small intestine
Clearance of Urea
- A Urea clearance device
Clearance of Phosphate
- A Phosphate clearance and balance device
Clearance of Guanidine
- A Guanidine clearance device
Time Regulation
- Enables detachment from the small intestine after a certain amount of time
- Experimenting with two systems:
  - Cyanoxilator: A tuneable cyanobacterial natural (sinusoidal) oscillator implemented in E. coli.
  - Reloxilator: A tuneable intracell-synchronized relaxation oscillator.

News and Updates.

@@ Line 241: / Line 241: @@
 * The mortality rate of patients undergoing maintenance hemodialysis remains unacceptably high.
 * An extremely high morbidity and a relatively low quality of life (due in part to a high level of dependence and unemployment) and high cost have also been observed.
-<br>'''How our project is divided:'''
+<br>'''Our Design:'''
+* After ingesting our BacToKidney capsule, it passes the through stomach without taking any action, nor being digested, and proceeds to the small intestine. Once in the small intestine, the [[Team:NYMU-Taipei/Project/pH Sensor|pH Sensor]] detects the change in pH and activates the clearance processes of [[Team:NYMU-Taipei/Project/Urea|Urea]], [[Team:NYMU-Taipei/Project/Phosphate|Phosphate]], and [[Team:NYMU-Taipei/Project/Guanidine|Guanidine]] from the body. To allow itself more time to perform its tasks, the [[Team:NYMU-Taipei/Project/pH Sensor|pH Sensor]] also activates the [[Team:NYMU-Taipei/Project/Attachment|Attachment]] process, making the capsule attach itself to the small intestine. After a pre-selected amount of time has passed (controlled by the [[Team:NYMU-Taipei/Project/Time Regulation|time regulating oscillators]]), the capsule detaches itself from the small intestine and exits the body.
+<br>'''The parts our project is made up of:'''
 * [[Team:NYMU-Taipei/Project/pH Sensor | pH Sensor]]
 ** A sensor of '''proton concentration (pH)'''