Team:ETH Zurich/Modeling/Overview

Overview on the modelling framework

This page is meant to give an introduction to the the overall modelling framework we have constructed in order to asses feasibility analysis, temporal scale details and other parameter estimations that regard our project setup. As introduced in the project overview section, four main components can be identified in the deviced mechanism. Accordingly, we divided the modelling framework in four modules that tackles the relative problematics. The first module is concerned with the analysis of restriction enzymes and their cutting pattern on E.Coli genome, the second module analysis the cell response to selection pressure and genome reduction from a system point of view, the third module adresses issue connected with the setting of the chemostat mechanism for the cultivation of colonies

is the use of Restryction Enzymes and Ligases as molecular mechanism for reducing the genome,

Modelling Framework

1) Restriction Enzymes Analysis	2) Genome Scale Analysis
3) Chemostat Selection Method	4) Switch Circuit