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Team:ETH Zurich/Project/Background
From 2008.igem.org
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| + | == Current approaches == | ||
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| + | As usual when takling engineering projects, two main approaches can be followed: '''bottom-up''' and '''top-down'''. | ||
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| + | In the first case we try to identify all the necessary functions for our system to work (in this case: to live). In this case we identify pathways to produce all necesary metabolites the cell needs, such as lipids, aminoacids, etc. A good example of this approach can be found in []. | ||
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| + | The second approach starts from a working syspem (such as a well characterized strain like K12). By identifying non-essential parts of the metabolism and deleting them, we reduce the complexity of the cell. | ||
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Revision as of 19:04, 25 October 2008
Current approachesAs usual when takling engineering projects, two main approaches can be followed: bottom-up and top-down. In the first case we try to identify all the necessary functions for our system to work (in this case: to live). In this case we identify pathways to produce all necesary metabolites the cell needs, such as lipids, aminoacids, etc. A good example of this approach can be found in []. The second approach starts from a working syspem (such as a well characterized strain like K12). By identifying non-essential parts of the metabolism and deleting them, we reduce the complexity of the cell.
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