Latest revision as of 03:55, 30 October 2008

	Home	The Team	E. nigma Project	Parts Submitted to the Registry	Notebook

Davidson College - Missouri Western State University

iGEM 2008

E. nigma: XOR Gates, a Bacterial Hash Function, and Viz-A-Brick

Our team designed, modeled, and constructed a bacterial computer that uses XOR logic to compute a cryptographic hash function. Hash functions are used to authenticate the integrity of a document by computing its digital fingerprint. Our bacterial computers are designed to recognize the presence or absence of two chemical signals via intercellular communication. Mathematical modeling of these computers has shown that our hash functions are difficult to corrupt. We designed and built a number of new parts, and improved and gained experience on existing parts. We also produced a graphical interface for exploring the Registry of Standard Biological Parts called Viz-A-Brick, and other web-based tools to improve the construction of new parts with BioBrick ends.

Highlights For Judges

New Parts Contributed to the Registry - we designed, built, and contributed 105 new parts to the Registry

Experience gained on new Registry parts - we measured the function of several of the new parts we designed, and some expectations were met

Improvement of pre-existing Registry parts - we redesigned the lac promoter and the lac repressor and measured an improvement in their functions

Online tools that support design of new BioBrick parts - we created online tools to aid in part design.

Viz-A-Brick: A new way to visualize the registry - we created a new interface to the Registry that addresses Human Practice issues associatated with navigating the expanding Registry

E. nigma Project - we designed and constructed several systems for using logic gates to compute hash functions in bacteria

iGEM 2008 powerpoint presentation Media:MWSU_Davidson_iGEM08.PPT

iGEM 2008 poster Media:MWSU_Davidson_iGEM08_poster.PPT

Funding - This collaborative project has received major support from National Science Foundation Grants #DMS-0733952 & 0733955, and was also supported by HHMI grant # 52006292, Davidson College DRI, the Davidson College Martin Genomics Program, the Missouri Western Foundation and the Missouri Western Office of Academic and Student Affairs.

Home	The Team	E. nigma Project	Parts Submitted to the Registry	Notebook

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-|[[Image:Example_logo.png|200px|center|frame]]
+![[Image:Spy1.jpg|30px]] <br>
+!align="center"|[[Team:Davidson-Missouri_Western|Home]]
-Students and faculty from Davidson College and Missouri Western State University are once again collaborating on a project for iGEM.  The 2008 team consists of one biology and one mathematics faculty mentor from each institution and students from both disciplines at both institutions, as well as one student from Hampton University and one from Spellman College. It is truly a multidisciplinary and multi-institution collaboration.  The picture above was taken July 3 on the steps of the Chambers Building on the Davidson College campus, following a week of intense, side-by-side collaboration.
+!align="center"|[[Team:Davidson-Missouri_Western/Team|The Team]]
-|[[Image:Chambers_TeamPic_070308.jpg|right|thumbnail|500px|The Davidson / Missouri Western synthetic biology team]]
+!align="center"|[[Team:Davidson-Missouri_Western/Project|''E. nigma'' Project]]
-|-
+!align="center"|[[Team:Davidson-Missouri_Western/New_Parts_Contributed_to_the_Registry|Parts Submitted to the Registry]]
-|
+!align="center"|[[Team:Davidson-Missouri_Western/Notebook|Notebook]]
 |}
+<font size = "6"><center>
+Davidson College - Missouri Western State University
+</center>
+<center>
+iGEM 2008
+</center></font>
+<center>
+[[Image:E_nigma_logo.jpg|400 px]] [[Image:vizabrick_logo.png|259 px]]
+<br>
+</center>
+''' ''E. nigma'': XOR Gates, a Bacterial Hash Function, and Viz-A-Brick'''
+Our team designed, modeled, and constructed a bacterial computer that uses XOR logic to compute a cryptographic hash function. Hash functions are used to authenticate the integrity of a document by computing its digital fingerprint.  Our bacterial computers are designed to recognize the presence or absence of two chemical signals via intercellular communication. Mathematical modeling of these computers has shown that our hash functions are difficult to corrupt. We designed and built a number of new parts, and improved and gained experience on existing parts.  We also produced a graphical interface for exploring the Registry of Standard Biological Parts called Viz-A-Brick, and other web-based tools to improve the construction of new parts with BioBrick ends.<br><br>
+<center>
+<span style="color:red">
+='''Highlights For Judges'''=
+</span>
+</center>
+'''[[Team:Davidson-Missouri_Western/New Parts Contributed to the Registry|New Parts Contributed to the Registry]]''' - we designed, built, and contributed 105 new parts to the Registry
+'''[[Team:Davidson-Missouri_Western/Experience Gained on New Registry Parts|Experience gained on new Registry parts]]''' - we measured the function of several of the new parts we designed, and some expectations were met
+'''[[Team:Davidson-Missouri_Western/Improvement of Pre-existing Registry Parts|Improvement of pre-existing Registry parts]]''' - we redesigned the lac promoter and the lac repressor and measured an improvement in their functions
+'''[[Team:Davidson-Missouri_Western/Online Tools that Support Design of New Biobrick Parts|Online tools that support design of new BioBrick parts]]''' - we created online tools to aid in part design.
+'''[[Team:Davidson-Missouri_Western/Viz-A-Brick: A New Way to Visualize the Registry|Viz-A-Brick: A new way to visualize the registry]]''' - we created a new interface to the Registry that addresses Human Practice issues associatated with navigating the expanding Registry
+'''[[Team:Davidson-Missouri_Western/Project|''E. nigma'' Project]]''' - we designed and constructed several systems for using logic gates to compute hash functions in bacteria
+<br/>
+i'''GEM 2008 powerpoint presentation''' [[Media:MWSU_Davidson_iGEM08.PPT]]
+'''iGEM 2008 poster'''  [[Media:MWSU_Davidson_iGEM08_poster.PPT]]
+'''Funding''' - This collaborative project has received major support from National Science Foundation Grants #DMS-0733952 & 0733955, and was also supported by HHMI grant # 52006292, Davidson College DRI, the Davidson College Martin Genomics Program, the Missouri Western Foundation and the Missouri Western Office of Academic and Student Affairs.
-Students and faculty from Davidson College and Missouri Western State University are once again collaborating on a project for iGEM.  The 2008 project, continuing in our theme of bacterial computing, focuses on cell-to-cell communication.
+<center>
+[[Image:Davidson_logo.JPG|140 px]]   &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;    [[Image:Nsflogo.jpg|59 px]]      [[Image:HHMI.gif]]      [[Image:Western_logo.JPG|140 px]]
+</center>
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 !align="center"|[[Team:Davidson-Missouri_Western|Home]]
 !align="center"|[[Team:Davidson-Missouri_Western/Team|The Team]]
-!align="center"|[[Team:Davidson-Missouri_Western/Project|The Project]]
+!align="center"|[[Team:Davidson-Missouri_Western/Project|''E. nigma'' Project]]
-!align="center"|[[Team:Davidson-Missouri_Western/Parts|Parts Submitted to the Registry]]
+!align="center"|[[Team:Davidson-Missouri_Western/New_Parts_Contributed_to_the_Registry|Parts Submitted to the Registry]]
-!align="center"|[[Team:Davidson-Missouri_Western/Modeling|Modeling]]
 !align="center"|[[Team:Davidson-Missouri_Western/Notebook|Notebook]]
 |}
-(''Or you can choose different headings.  But you must have a team page, a project page, and a notebook page.'')

Team:Davidson-Missouri Western

From 2008.igem.org

Latest revision as of 03:55, 30 October 2008

Highlights For Judges