Team:BCCS-Bristol/Parts

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!align="center"|[[Team:BCCS-Bristol/Parts|Submitted Parts]]
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!align="center"|[[Team:BCCS-Bristol/Modeling|Modelling]]
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!align="center"|[[Team:BCCS-Bristol/Notebook|Wet Lab]]
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== In Progress ==
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== Submitted Bio-Bricks ==
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[http://partsregistry.org/Part:BBa_K135000 BBa_K135000]
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This BioBrick contains pCpxR, a promoter which is responsive to phosphorylated CpxR (CpxR-P). Upon adhesion to hydrophobic surfaces, the CpxRA two-component system is activated. The inner membrane histidine kinase CpxA phosphorylates CpxR which then becomes active and regulates a number of target genes. This promoter is therefore sensitive to adhesion to hydrophobic surfaces.
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[http://partsregistry.org/Part:BBa_K135001 BBa_K135001]
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In this part, the CpxR-P responsive promoter pCpxR is fused to the BioBrick [http://partsregistry.org/Part:BBa_E0840 BBa_E0840] which encodes GFP. Thus, GFP is expressed after binding to hydrophobic surfaces (see also [http://partsregistry.org/Part:BBa_K135000 BBa_K135000] for further explanations). 
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No parts submitted so far.
 
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== Approved ==
 
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No parts submitted so far.
 
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Latest revision as of 22:36, 28 October 2008

BCCS-Parts-Header 01.jpg BCCS-Parts-Header 02.jpg BCCS-Parts-Header 03.jpg

Submitted Bio-Bricks

[http://partsregistry.org/Part:BBa_K135000 BBa_K135000]

This BioBrick contains pCpxR, a promoter which is responsive to phosphorylated CpxR (CpxR-P). Upon adhesion to hydrophobic surfaces, the CpxRA two-component system is activated. The inner membrane histidine kinase CpxA phosphorylates CpxR which then becomes active and regulates a number of target genes. This promoter is therefore sensitive to adhesion to hydrophobic surfaces.


[http://partsregistry.org/Part:BBa_K135001 BBa_K135001]

In this part, the CpxR-P responsive promoter pCpxR is fused to the BioBrick [http://partsregistry.org/Part:BBa_E0840 BBa_E0840] which encodes GFP. Thus, GFP is expressed after binding to hydrophobic surfaces (see also [http://partsregistry.org/Part:BBa_K135000 BBa_K135000] for further explanations).