Team:Imperial College

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Latest revision as of 09:06, 30 October 2008

For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.

Pushed for time? Project Summary | Achievements | Growing Clothes: BioCouture

Overview

The following video is a simplified representation of how we want our system to work...

First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
Finally, when our bacteria are stationary in the correct location, the biomaterial production is triggered. These biomaterials can self-assemble to form a 3D bio-scaffold.

Please continue on to our project pages - you may wish to start with our >>> Project Specifications >>>

The Imperial College Team 2008 has received sponsorship from a number of generous companies. We are grateful for their kind support.

We would also like to thank the members of the Center for Structural Biology for their help and support during our iGEM project.

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-<html><center><img width="700px" src="https://static.igem.org/mediawiki/2008/9/94/Imperial_2008_Title.png"></center>
+<html><center><img width="830px" src="https://static.igem.org/mediawiki/2008/9/94/Imperial_2008_Title.png"></center><font size="4pt"></html><center>'''<br>For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium ''Bacillus subtilis'' as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.'''<br><br><html></font>
-<font size="4pt"></html><center>'''For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.'''<html></font><br><br><table style="background-color:transparent;color:#2B48B3;"><tr><td width="50%" style="border:1px solid #2B48B3;"><br><br><img width="230px" src="https://static.igem.org/mediawiki/2008/c/cf/Implementation.PNG"><br>Pushed for time? For a basic overview of our project, you can look at the Summer Summary page.</td><td width="360px"><img width="350px" src="http://i59.photobucket.com/albums/g305/Timpski/Logo1.png"></td><td width="50%" style="border:1px solid #2B48B3;"><br><img width="104px" src="https://static.igem.org/mediawiki/2008/8/8e/Biocouture.PNG"><img width="105px" src="https://static.igem.org/mediawiki/2008/a/a4/Biocouture2.PNG"><br>An example of a useful application for our project is Biocouture. Visit our page on it to see what it's about!</td></tr></table></html></center>
+<table style="color:#2B48B3;background-color:transparent;"><tr><td><img style="vertical-align:center;" width="380px" src="http://i59.photobucket.com/albums/g305/Timpski/Logo1.png"></td>
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+<!--<td style="text-align:center;"><br><i><font size="3pt" style="border:2px solid;padding:7px;"><b><a target="_blank" href="https://2008.igem.org/Team:Imperial_College/BioBricks">45 B. subtilis BioBricks submitted!</a></b></font><br><br><font size="3pt" style="border:2px solid;padding:7px;"><b><a target="_blank" href="https://2008.igem.org/Team:Imperial_College/Major_Results">BioBrick Characterisation</a></b></font><br><br><font size="3pt" style="border:2px solid;padding:7px;"><b>Chassis Characterisation</b></font><br><br><font size="3pt" style="border:2px solid;padding:7px;">Cell <b><a target="_blank" href="https://2008.igem.org/Team:Imperial_College/Motility">motility tracking</a></b></font><br><br><font size="3pt" style="border:2px solid;padding:7px;">Extensive <b><a target="_blank" href="https://2008.igem.org/Team:Imperial_College/Dry_Lab">modelling</a></b></font></i>-->
+</td></tr></table><br><hr><center><font size="4pt" style="border:0px solid;padding:10px;">Pushed for time? <b><a target="_blank" href="https://2008.igem.org/Team:Imperial_College/Summary">Project Summary</a> | <a target="_blank" href="https://2008.igem.org/Team:Imperial_College/Summary#Results">Achievements</a> | Growing Clothes: <b><a target="_blank" href="https://2008.igem.org/Team:Imperial_College/Cellulose">BioCouture</a></b></font></center><hr><br></html>
 |}}
-{{Imperial/Box1|'''<html><font size=6px>Overview</font></html>'''|The principle concepts of the Biofabricator subtilis project are:
+{{Imperial/Box1|'''<html><font size=6px>Overview</font></html>'''|
+The following video is a simplified representation of how we want our system to work...
+<html><center><object width="425" height="350"> <param name="movie" value="http://www.youtube.com/v/pqEmKkY5DxA"> </param> <embed src="http://www.youtube.com/v/pqEmKkY5DxA" type="application/x-shockwave-flash" width="425" height="350"> </embed> </object></center></html>
 *First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
 *Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
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 <html><center><img width="800px" src="http://i59.photobucket.com/albums/g305/Timpski/Comic_No_Title.png"></center></html>
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-<center>'''<html><font size=4px>Please continue on to our project pages - you may want to start with our</font></html>'''<br> [[Team:Imperial_College/Project/| '''<html><font size=4px> >>> Project Specifications >>></font></html>''']]</center>
+'''<html><center><font size=4px></html>Please continue on to our project pages - you may wish to start with our [[Team:Imperial_College/Project |>>> Project Specifications >>>''']]<html></font></center></html>
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 The Imperial College Team 2008 has received sponsorship from a number of generous companies. We are grateful for their kind support.
-<html><center><a href="http://www.bio-rad.com/"><img height="40px" src="http://i59.photobucket.com/albums/g305/Timpski/Biorad.png"></a><a href="http://www.fisher.co.uk/"><img height="50px" src="http://i59.photobucket.com/albums/g305/Timpski/Fisher.png"></a><a href="http://www.geneart.com/"><img height="25px" src="http://i59.photobucket.com/albums/g305/Timpski/Geneart.png"></a><a href="http://www.vwr.com/index.htm"><img height="50px" src="http://i59.photobucket.com/albums/g305/Timpski/VWR.png"></a></center></html>
+<html><center><a href="http://www.bio-rad.com/"><img height="40px" src="http://i59.photobucket.com/albums/g305/Timpski/Biorad.png"></a><a href="http://www.fisher.co.uk/"><img height="50px" src="http://i59.photobucket.com/albums/g305/Timpski/Fisher.png"></a><a href="http://www.geneart.com/"><img height="25px" src="http://i59.photobucket.com/albums/g305/Timpski/Geneart.png"></a><a href="http://www.vwr.com/index.htm"><img height="50px" src="http://i59.photobucket.com/albums/g305/Timpski/VWR.png"></a></center>
+<center>We would also like to thank the members of the Center for Structural Biology for their help and support during our iGEM project.</center></html>
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