Team:Utah State

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'''PHB'''
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The increasing cost and negative environmental effect of fossil hydrocarbon-derived conventional plastics has escalated the need for economically realistic alternatives.  Polyhydroxyalkanoates (PHAs) are a class of microbially synthesized, biodegradable thermoplastics that exhibit material properties comparable to those of conventional plastics. The Utah State University IGEM team project is focused on creating an efficient system for monitoring PHA production in recombinant microorganisms.
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The Utah State University iGEM team project is focused on creating an efficient system for monitoring of PHA production in microorganisms. The major goal of our research is to develop and optimize a method, using fluorescent proteins, for the detection of maximum product yield of polyhydroxybutyrate (PHB, a bioplastic) in recombinant E. coli and in Cupriavidus necator. In order to develop an optimal PHB detection system, we focused on the identification of the most efficient reporter genes and the best promoter sequences that would allow our reporter to indicate when PHB production was maximized.
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Utah State University is proud to be involved for the first time in the 2008 iGEM competition. The 2008 USU iGEM team consists of graduate and undergraduate students in Biological Engineering, as well as two high school students, working under the supervision of professors with backgrounds in Biological Engineering, Electrical Engineering, Biology, and Microbiology. Prior to this project, none of the undergraduate or high school students had experience with genetic engineering or synthetic biology. This project provided a great opportunity for these students to learn about synthetic biology and its potential, as well as to gain a great deal of hands on experience with laboratory methods. Through team meetings and working closely together in the lab, team members were also provided with opportunities to get to know each other and the specific project material.  
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This project was selected because of its potential to make the PHB production process more efficient and cost effective by creating a simple system for determining the optimum time for PHB extraction.
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Though many project topics were discussed, the team chose the project for developing a method of monitoring polyhydroxybutyrate production in microorganisms by inserting a reporter in the PHB cassette. This project was selected because of its potential to make the PHB production process more efficient and cost effective by creating a simple system for determining the optimum time for PHB extraction. This project was carried out from May to October of 2008.
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USU is located in Logan UT and is nestled in the beautiful mountains of Cache Valley. For those interested in a great education and are looking for amazing outdoor adventures and recreation, USU is perfect!!
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USU is located in Logan, Utah and is nestled in the beautiful mountains of Cache Valley. For those interested in a great education and are looking for amazing skiing and other outdoor adventures and recreation, USU is perfect!
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<!--- The Mission, Experiments --->
 
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'''ABOUT USU'''
 

Latest revision as of 03:52, 30 October 2008

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Utah State University is proud to be involved for the first time in the 2008 iGEM competition. The 2008 USU iGEM team consists of graduate and undergraduate students in Biological Engineering, as well as two high school students, working under the supervision of professors with backgrounds in Biological Engineering, Electrical Engineering, Biology, and Microbiology. Prior to this project, none of the undergraduate or high school students had experience with genetic engineering or synthetic biology. This project provided a great opportunity for these students to learn about synthetic biology and its potential, as well as to gain a great deal of hands on experience with laboratory methods. Through team meetings and working closely together in the lab, team members were also provided with opportunities to get to know each other and the specific project material.

Though many project topics were discussed, the team chose the project for developing a method of monitoring polyhydroxybutyrate production in microorganisms by inserting a reporter in the PHB cassette. This project was selected because of its potential to make the PHB production process more efficient and cost effective by creating a simple system for determining the optimum time for PHB extraction. This project was carried out from May to October of 2008.


USU is located in Logan, Utah and is nestled in the beautiful mountains of Cache Valley. For those interested in a great education and are looking for amazing skiing and other outdoor adventures and recreation, USU is perfect!

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