Team:Michigan/Project/Modeling/Model2.html

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*kr= dissociation rate of NifA/NifL complex
*kr= dissociation rate of NifA/NifL complex
*any d= degradation rate of that species
*any d= degradation rate of that species
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*kb:rate of complex formation (i.e. dimerization, formation of tetramers/hexamers)
 +
*kb2: dissociation rate of such complexes given above
 +
[https://2008.igem.org/Team:Michigan/Project/Modeling Back to Modeling]
[https://2008.igem.org/Team:Michigan/Project/Modeling Back to Modeling]
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Revision as of 01:59, 30 October 2008


Michigan iGEM website header.jpg

HOME THE TEAM THE PROJECT REGISTRY PARTS NOTEBOOK


Sequestillator Model 2: A More Complicated Model

While Model 1 gave us some important results (mainly: need a low Kd for oscillations to occur) , we decided to look at more complete model that accounted for some of the dimerizations the proteins undergo:

Model2Equations.png

Parameters/functions

  • a= production of NifA
  • kf= binding rate of NifA and NifL
  • kr= dissociation rate of NifA/NifL complex
  • any d= degradation rate of that species
  • kb:rate of complex formation (i.e. dimerization, formation of tetramers/hexamers)
  • kb2: dissociation rate of such complexes given above


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