Team:Chiba/Project

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Project overview

E.coli time manager

Abstract:

We control the timing of gene expression by using multiple signaling devices.To this end,we utilize molecules associated with Quorum sensing, a phenomenon that allows bacteria to communicate with each other.Our project uses two classes of bacteria: senders and receivers. Senders produce　signaling molecules, and　Receivers are activated only after a particular concentration of this　molecule is reached.Although different quorum sensing species have slightly different signaling molecules, these molecules are not completely specific to their hosts and cross-species reactivity is observed.Communication using non-endogenous molecules is less sensitive, andrequires a higher signal concentration to take effect.This results in slower activation of receivers.

Project Details

Part 2 The Experiments

Part 3

Results

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 '''Abstract:'''
- We control the timing of gene expression by using multiple signaling devices.To this end,we utilize molecules associated with Quorum sensing, a phenomenon that allows bacteria to communicate with each other.Our project uses two classes of bacteria: senders and receivers. Senders produce　signaling molecules, and　Receivers are activated only after a particular concentration of this　molecule is reached.Although different quorum sensing species have slightly different signaling molecules, these molecules are not completely specific to their hosts and cross-species reactivity is observed.Communication using non-endogenous molecules is less sensitive, andrequires a higher signal concentration to take effect.This results in slower activation of receivers.
+:We control the timing of gene expression by using multiple signaling devices.To this end,we utilize molecules associated with Quorum sensing, a phenomenon that allows bacteria to communicate with each other.Our project uses two classes of bacteria: senders and receivers. Senders produce　signaling molecules, and　Receivers are activated only after a particular concentration of this　molecule is reached.Although different quorum sensing species have slightly different signaling molecules, these molecules are not completely specific to their hosts and cross-species reactivity is observed.Communication using non-endogenous molecules is less sensitive, andrequires a higher signal concentration to take effect.This results in slower activation of receivers.
 == Project Details==