Team:Imperial College

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<font size="4pt"></html><center>'''For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.'''<html></font><br><br><img width="350px" src="http://i59.photobucket.com/albums/g305/Timpski/Logo1.png"></html></center>
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<font size="4pt"></html><center>'''For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.'''<html></font><br><br><table style="background-color:transparent;color:#2B48B3;"><tr><td width="50%" style="border:1px solid #2B48B3;"><br><br><img width="230px" src="https://static.igem.org/mediawiki/2008/c/cf/Implementation.PNG"><br>Pushed for time? For a basic overview of our project, you can look at the Summer Summary page.</td><td width="360px"><img width="350px" src="http://i59.photobucket.com/albums/g305/Timpski/Logo1.png"></td><td width="50%" style="border:1px solid #2B48B3;"><br><img width="104px" src="https://static.igem.org/mediawiki/2008/8/8e/Biocouture.PNG"><img width="105px" src="https://static.igem.org/mediawiki/2008/a/a4/Biocouture2.PNG"><br>An example of a useful application for our project is Biocouture. Visit our page on it to see what it's about!</td></tr></table></html></center>
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Revision as of 17:05, 24 October 2008


For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.




Pushed for time? For a basic overview of our project, you can look at the Summer Summary page.

An example of a useful application for our project is Biocouture. Visit our page on it to see what it's about!

Overview

The principle concepts of the Biofabricator subtilis project are:

  • First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
  • Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
  • Finally, when our bacteria are stationary in the correct location, the biomaterial production is triggered. These biomaterials can self-assemble to form a 3D bio-scaffold.


Please continue on to our project pages - you may want to start with our
>>> Project Specifications >>>


The Imperial College Team 2008 has received sponsorship from a number of generous companies. We are grateful for their kind support.



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