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Team:Rice University
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-Normally used as a defense mechanism in plants in response to fungal pathogens and UV irradiation. <BR> | -Normally used as a defense mechanism in plants in response to fungal pathogens and UV irradiation. <BR> | ||
-Main source in human diet is red wine, but significant amounts are also found in grape juice, peanuts, cranberry juice, and others. | -Main source in human diet is red wine, but significant amounts are also found in grape juice, peanuts, cranberry juice, and others. | ||
| - | [[Image:trans-resveratrol.jpg|left]] | + | [[Image:trans-resveratrol.jpg|left]] |
| + | <BR><BR><BR><BR><BR><BR><BR><BR><BR><BR> | ||
| + | Why resveratrol in beer? <BR> | ||
| + | -Beer made up 85.8% of all alcoholic beverage consumption (in total volume) in 2005. <BR> | ||
| + | -->Annual per capita consumption of Beer (2005) = ~20 gallons <BR> | ||
| + | -->Annual per capita consumption of Wine (2005) = ~2.5 gallons <BR> | ||
| + | |||
| + | -If resveratrol can be produced during fermentation, it provides an additional health benefit at no additional cost. <BR> | ||
| + | -->The resveratrol is produced in a ready-to-consume format! <BR> | ||
| + | -->Dark and anaerobic conditions required for fermentation improve resveratrol stability. <BR> | ||
| + | [[Image:winetobeer.jpg|right]] | ||
<BR><BR><BR><BR><BR><BR><BR><BR><BR><BR> | <BR><BR><BR><BR><BR><BR><BR><BR><BR><BR> | ||
Revision as of 21:09, 25 October 2008
Welcome to Rice University's 2008 iGEM wiki page.
Our project for this year is BIOBEER, where we are genetically engineering the biosynthetic pathway for resveratrol production into a brewing yeast strain. Resveratrol has been shown to have a plethora of health benefits, including anti-cancer and anti-viral activity, cardio- and neuro-protective effects, modulation of diabetes, and anti-aging effects. Although research has been done previously to produce resveratrol in various organisms, no one to date has developed a yeast strain able to synthesize resveratrol in a de novo manner. We are going one step further, characterizing resveratrol production during anaerobic fermentation with the intent of creating a beer that contains all the health benefits of wine. Get ready for resveratrol in a fizzy ready-to-consume beverage!
(More detailed descriptions of projects to be added.)
BioBeer: Producing Resveratrol During Fermentation in Beer
Resveratrol
-First identified as the active component in C. quinquangulata (cinnamon) extract responsible for anti-inflammatory properties.
-Normally used as a defense mechanism in plants in response to fungal pathogens and UV irradiation.
-Main source in human diet is red wine, but significant amounts are also found in grape juice, peanuts, cranberry juice, and others.
Why resveratrol in beer?
-Beer made up 85.8% of all alcoholic beverage consumption (in total volume) in 2005.
-->Annual per capita consumption of Beer (2005) = ~20 gallons
-->Annual per capita consumption of Wine (2005) = ~2.5 gallons
-If resveratrol can be produced during fermentation, it provides an additional health benefit at no additional cost.
-->The resveratrol is produced in a ready-to-consume format!
-->Dark and anaerobic conditions required for fermentation improve resveratrol stability.
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