Team:Imperial College/Genetic Circuit Details

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{{Imperial/Box1|Simple Model ({{ref|1}}) |
{{Imperial/Box1|Simple Model ({{ref|1}}) |
====Equilibria====
====Equilibria====
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[[Image:Simple_model_equilibria.jpg]]
====Equations====
====Equations====

Revision as of 23:23, 28 October 2008


Simple Model (1)

Equilibria

Simple model equilibria.jpg

Equations


More Sophisticated Model(2)

Equilibria

Assumptions:

No intermediary P-IPTG-LacI complex is formed.

We assumed 2 LacI molecules bind to the promoter.

Equations

Qualitative effect of parameters on behaviour


References
  1. Kuhlman T, Zhang Z, Saier MH Jr, & Hwa T (2007) Combinatorial transcriptional control of the lactose operon of Escherichia coli. - PNAS 104 (14) 6043-6048
  2. Alon, U (2006) An Introduction to Systems Biology: Design Principles of Biological Circuits - Chapman & Hall/Crc Mathematical and Computational Biology