Team:Davidson-Missouri Western/Project

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Home	The Team	E. nigma Project	Parts Submitted to the Registry	Notebook

E. nigma Project: Using E. coli to compute values of a cryptographic hash function

Our multidisciplinary team conducted a project that drew expertise from biology and mathematics to explore the possibility of designing, modeling, constructing, and testing logic gates that would enable bacteria to compute a hash function. The links below provide documentation of the diverse outcomes of our research, illustrating not only the feasibility of bacterial computation but the ability of undergraduates students to contribute to an important emerging field.

What is a Hash Function?

Hash functions and biological systems

Our Models

Analysis of our Models

Matlab files

Future work

Define XOR logic gates and how it was used with biological inputs and outputs

XOR and Autoinducers

Describe different design architectures

DNA Encoded XOR Gates

Describe cellular communication systems used

Cellular Communication Systems

[http://partsregistry.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2008&group=Davidson-Missouri_Western parts contributed ]

Constructs tested

Systems for sending and receiving

Discuss need for delayed growth (common problem with many projects in the past)

Time-Delayed Growth ([http://www.bio.davidson.edu/courses/genomics/2008/DeLoache/TimeDelayedWithTimes.mov See the QT Movie])

Present Hybrid Promoter Designs cartoon fashion (3 major different types)

Hybrid Promoters

Show data we have with new parts

Experimental data on XOR gate

Home	The Team	E. nigma Project	Parts Submitted to the Registry	Notebook

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