Team:Imperial College/Genetic Circuit Details
From 2008.igem.org
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[[Image:Simple_model_steady_state_pre_induction.jpg|300px]] | [[Image:Simple_model_steady_state_pre_induction.jpg|300px]] | ||
- | Note: | + | Note: k<sub>1</sub> and k<sub>8</sub> represent the rate of transcription through the constitutive promoter upstream of LacI and the promoter upstream of GFP respectively. |
- | + | d<sub>1</sub> and d<sub>GFP</sub> represent the degradation rates of LacI and GFP respectively. | |
- | + | k<sub>ß</sub> is defined as k<sub>4</sub>/k<sub>5</sub>. | |
To describe the change in concentration of the interacting species over time we used the following system of differential equations: | To describe the change in concentration of the interacting species over time we used the following system of differential equations: | ||
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{{Imperial/Box2|| | {{Imperial/Box2|| | ||
===== References ===== | ===== References ===== | ||
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#{{FormatRef|Alon, U|2006|An Introduction to Systems Biology: Design Principles of Biological Circuits|||Chapman & Hall/Crc Mathematical and Computational Biology}} | #{{FormatRef|Alon, U|2006|An Introduction to Systems Biology: Design Principles of Biological Circuits|||Chapman & Hall/Crc Mathematical and Computational Biology}} | ||
+ | #{{FormatRef|Kuhlman T, Zhang Z, Saier MH Jr, & Hwa T|2007|Combinatorial transcriptional control of the lactose operon of Escherichia coli.|PNAS 104 (14)|6043-6048|}} | ||
|}} | |}} | ||
{{Imperial/EndPage|Genetic_Circuit|Genetic_Circuit}} | {{Imperial/EndPage|Genetic_Circuit|Genetic_Circuit}} |
Revision as of 18:49, 29 October 2008
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