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Team:Newcastle University/Mark's Lab Journal
From 2008.igem.org
(New page: '''16/05/2008''' Following Thursdays meeting I have been researching into Quorum sensing peptides that are unique to Staphylococcus aureus. After consulting the literature I have noted th...)
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Revision as of 15:16, 11 July 2008
16/05/2008
Following Thursdays meeting I have been researching into Quorum sensing peptides that are unique to Staphylococcus aureus. After consulting the literature I have noted the presence of four Quorum sensing systems. They are agr, sae, artRS and SrrAB. The relevant papers are linked to below. Previously I discovered that there were four different autoinducing peptides in Staphylococcus aureus. However it has now become clear that these are indeed unique to S. aureus, and are not present (in the same sequence) in any other member of the Staph species. The agrC receptors also have different corresponding conformational groups. It may be possible to use all four AIP's and agrC's as a S. aureus biosensor.
At this point I went on to retrieve the sequences using the NCBI and EBI databases.
