Team:Chiba/Project

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Project Objection

Harmful radiation such as UV and X-ray are transient and non-traceable. However, their effects accumulate over time. It is therefore necessary to know the level of exposure (strength of ray multiplied with time of exposure). In this year we are constructing a genetic system that measure the radiation level.

Our system consists of two components. Circuit A senses radiation (via SOS promoter systems) and generates message molecules. The molecules must be stable (non-degradable) and it get accumulated over time. Circuit B senses the level of message molecule, when ordered. We are testing various chemical sensors for the best use of this system.

Aside from the exposure to the sunlight or radioactive compounds, there are so many need for measuring cumulative total value in this world. Our system is quite modular, and it can reform to be a calculator of various other things. Included are the toxic pollutants (bad for health), molecular oxygen (bad for food storage), improper high temperature (bad for food storage), energy consumed (bad for earth), or debt or speeding tickets (bad for our purse).

Project Details

Part 2 The Experiments

Part 3

Results

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 == '''Project Objection''' ==
-Living things, environment and chemical samples are exposed to an input like as UV or radiation, which is "volatile" but whose effects to them accumulate in our body, environment and samples. We would like to know the total strength of exposure to the input, not only its existence.
-To do this, we construct two genetic circuits. Circuit A synthesizes less-metabolic and stable molecules linearly to the strength of the input. The information of the total amount of the strength of the past input won't be deleted due to less-metabolicity and stability of these molecules. And they play a role as cell-cell communication signals. Circuit B senses the concentration of the signals and report how much strength have exposed to them. In this way, we can measure the total strength of exposure to UV, radiation, environmental pollutants and various kinds of substances as well just by changing the input sensor of E.coli A.
+Harmful radiation such as UV and X-ray are transient and non-traceable. However, their effects accumulate over time. It is therefore necessary to know the level of exposure (strength of ray multiplied with time of exposure). In this year we are constructing a genetic system that measure the radiation level.
+Our system consists of two components. Circuit A senses radiation (via SOS promoter systems) and generates message molecules.  The molecules must be stable (non-degradable) and it get accumulated over time. Circuit B senses the level of message molecule, when ordered. We are testing various chemical sensors for the best use of this system.
+Aside from the exposure to the sunlight or radioactive compounds, there are so many need for measuring cumulative total value in this world. Our system is quite modular, and it can reform to be a calculator of various other things. Included are the toxic pollutants (bad for health), molecular oxygen (bad for food storage), improper high temperature (bad for food storage), energy consumed (bad for earth), or debt or speeding tickets (bad for our purse).
 == Project Details==