Team:Imperial College

From 2008.igem.org

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{{Imperial/Box1|Overview|*First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
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{{Imperial/Box1|Overview|The principle concepts of the Biofabricator subtilis project are:
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*First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
*Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
*Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
*Finally, when our bacteria are stationary in the correct location, the biomaterial production is triggered. These biomaterials can self-assemble to form a 3D bio-scaffold.
*Finally, when our bacteria are stationary in the correct location, the biomaterial production is triggered. These biomaterials can self-assemble to form a 3D bio-scaffold.
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Please continue on to our project pages - you may want to start with our [[Team:Imperial_College/Project/| '''>>> Project Specifications >>>''']]}}
Please continue on to our project pages - you may want to start with our [[Team:Imperial_College/Project/| '''>>> Project Specifications >>>''']]}}

Revision as of 20:26, 19 October 2008


For the 2008 iGEM competition, the Imperial College Team aims to develop a genetically-engineered Biofabricator, using the Gram-positive bacterium Bacillus subtilis as our chassis. Our Biofabricator aims to produce self-assembling biomaterials in specified 3D shapes, using light as the trigger.

Overview

The principle concepts of the Biofabricator subtilis project are:

  • First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography.
  • Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein.
  • Finally, when our bacteria are stationary in the correct location, the biomaterial production is triggered. These biomaterials can self-assemble to form a 3D bio-scaffold.

Please continue on to our project pages - you may want to start with our >>> Project Specifications >>>



The Imperial College Team 2008 has received sponsorship from a number of generous companies. We are grateful for their kind support.



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