Team:MIT
From 2008.igem.org
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{|align="justify" | {|align="justify" | ||
- | | | + | |<div id="mainpage"> |
+ | |||
+ | <hr class=divider> | ||
+ | <div id="about"> | ||
+ | {| | ||
+ | | rowspan=2 | [[Image:team-logo.jpg|218px]] | ||
+ | [[Image:Mit-blackred-header2.gif|194px http://web.mit.edu]] | ||
+ | | | ||
+ | '''Welcome to the MIT team Wiki for iGEM 2008''' | ||
+ | *'''iGEM''' is the international genetically engineered machines competition. | ||
+ | *The objective of the competition is to design and build an engineered biological system using [http://en.wikipedia.org/wiki/DNA DNA]. | ||
+ | *To see examples of the '''amazing possibilities''' of iGEM, check out last years [http://parts.mit.edu/igem07/index.php/Main_Page iGEM page] | ||
+ | *Read our '''promotional brochure''' to learn about synthetic biology at MIT ([[media:mit_igem2008_brochure_front.gif|front]] and [[media:mit_igem2008_brochure_back.gif|back]]). | ||
+ | *iGEM at MIT is possible because of '''outside support''', contact Tom Knight (tk [at] mit.edu) to help out! | ||
+ | |} | ||
+ | </div> | ||
+ | <hr class=divider> | ||
+ | |||
+ | {| cellspacing="5" | ||
+ | |width="250px" class="green3" | | ||
+ | <!-- RESOURCES HEADER with edit link--> | ||
+ | <h3><html> | ||
+ | <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> | ||
+ | </html>Resources</h3> | ||
+ | <hr/> | ||
+ | <!-- END RESOURCES HEADER--> | ||
+ | Interested in learning more about iGEM 2008? Explore below for an example of what's possible. | ||
+ | |||
+ | For more info on this year's iGEM please see [https://2008.igem.org 2008.igem.org]. | ||
+ | |||
+ | Many more valuable links and helpful tidbits are available at the [http://parts.mit.edu/wiki/index.php/Resources iGEM Resources page] | ||
+ | |||
+ | ===For visitors=== | ||
+ | *Read more about [[Synthetic Biology|engineering biology]]. | ||
+ | *[http://stellar.mit.edu/S/course/20/sp08/20.020/ 20.020: MIT's introduction to bioengineering design] | ||
+ | |||
+ | ===External links=== | ||
+ | *[[iGEM|iGEM on OpenWetWare]] | ||
+ | *[http://parts.mit.edu/registry BioBricks Parts registry] | ||
+ | *[http://parts.mit.edu/igem07/index.php/Main_Page Official iGEM 2007 wiki] | ||
+ | *[http://parts.mit.edu/igem Official iGEM 2006 wiki] | ||
+ | *[http://openwetware.org/wiki/IGEM:MIT/2007 MIT 2007 Wiki] | ||
+ | *[http://parts.mit.edu/wiki/index.php/MIT_2006 MIT 2006 Wiki] | ||
+ | *BioBricks parts contributed by MIT: | ||
+ | **[http://parts.mit.edu/registry/index.php/Part:BBa_I728005 OmpC Surface Display] | ||
+ | **[http://parts.mit.edu/registry/index.php/Part:BBa_I728004 CPX Surface Display] | ||
+ | *[http://openwetware.org/wiki/20.109(S08) 20.109 instructions (2008)] | ||
+ | |||
+ | ===Internal links=== | ||
+ | *'''[[../2008/Notebook/Yogurt|Team Notebook]]''' | ||
+ | |||
+ | ===Protocols=== | ||
+ | *[http://openwetware.org/wiki/Endy:DNA_ligation_using_T4_DNA_ligase T4 ligation] | ||
+ | *[http://openwetware.org/wiki/TOP10_chemically_competent_cells Top10 chem competent cell transformation] | ||
+ | *[http://web.mit.edu/biopolymers/www/DNA.html DNA sequencing] | ||
+ | *[http://openwetware.org/wiki/Endy_pcr PCR] | ||
+ | *[http://openwetware.org/wiki/Knight:Restriction_Digest Restriction Digests] | ||
+ | |||
+ | ===Good Lab Citizenship=== | ||
+ | *Go over the [[DOs_and_DONTs_of_Good_Lab_Citizenship|Do's and Dont's of Good Lab Citizenship]] | ||
+ | |||
+ | ===Wiki editing resources=== | ||
+ | *[[Simple_wiki_editing_examples| Simple wiki editing examples]] | ||
+ | *[http://en.wikipedia.org/wiki/Wikipedia:How_to_edit_a_page How to edit a page (extended - wikipedia)] | ||
+ | *[http://www.mediawiki.org/wiki/Help:Images Help with images (wikipedia)] | ||
+ | *[http://en.wikipedia.org/wiki/Help:Table Help with tables (wikipedia)] | ||
+ | |||
+ | |width="350px" class="green2" | | ||
+ | <!-- INFORMATION HEADER with edit link--> | ||
+ | <h3><html> | ||
+ | <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="INFORMATION" border="0"> | ||
+ | </html>Information</h3> | ||
+ | <hr/> | ||
+ | <!-- END INFORMATION HEADER with edit link--> | ||
+ | |||
+ | |||
+ | === Want to help out the iGEM team? === | ||
+ | *iGEM at MIT is partly supported by the [http://web.mit.edu/urop/basicinfo/ Undergraduate Research Opportunity Program] and faculty including Drew Endy and Tom Knight. | ||
+ | *We guarantee UROP funding for undergrads. We need help to continue supporting undergrads, paying registration fees, and supplying lab reagents, contact [[Tom Knight]] to help out! | ||
+ | *'''Read more''' about our team on our '''[[/Notebook/Fundraise|fundraising notebook]]'''. | ||
+ | |||
+ | |||
+ | === Want to join the iGEM team? === | ||
+ | *'''Graduate''' students interested in advising the team should email '''grads [AT] igem.mit.edu''' | ||
+ | *'''Undergraduate''' students should get in touch during IAP or Spring of 2009! | ||
+ | |||
+ | |||
+ | |||
+ | ===Schedule=== | ||
+ | *April 10 - UROP funding deadline | ||
+ | *April 18 - iGEM registration opens | ||
+ | *May 3 - Teachers Workshop, MIT, USA | ||
+ | *May 9 - Registration closes | ||
+ | *June 9 - Summer term, lab work begins | ||
+ | *June 15 - Team rosters due | ||
+ | *July 1 - Registration fee due | ||
+ | *August 1 - Team project descriptions due | ||
+ | *August 19 - Summer term ends | ||
+ | *September 1 - Final team roster due | ||
+ | *October 1 - Jamboree attendance fees due | ||
+ | *October 15 - Project Summary form due | ||
+ | *October 29 - Project and part documentation due | ||
+ | *October 29 - BioBrick Part DNA received by the Registry | ||
+ | *November 8-9 - iGEM competition Jamboree, MIT, USA | ||
+ | |||
+ | <html> | ||
+ | <script language="JAVASCRIPT"><!-- update your browser, silly--> | ||
+ | Today = new Date(); | ||
+ | Jamboree = new Date("November 8, 2008"); | ||
+ | msInADay = 1000 * 60 * 60 * 24; | ||
+ | display = Math.floor((Jamboree.getTime() - Today.getTime())/msInADay); | ||
+ | document.write("There are " + display +" days left until the Jamboree!"); | ||
+ | // </script> | ||
+ | </html> | ||
+ | |||
+ | |||
+ | |||
+ | ---- | ||
+ | |||
+ | ===Brainstorming=== | ||
+ | |||
+ | *'''[[/Notebook/Yogurt/Brainstorming|Brainstorming]] | ||
+ | |||
+ | ===Meeting Logistics=== | ||
+ | *'''[[/Room Reservations|Room Reservations]]''' | ||
+ | *'''[[/Onduty|Gradvisor "On Duty" Shifts]]''' | ||
+ | *'''[[Technical Overseers|Technical Overseers]]''' | ||
+ | |||
+ | |||
+ | |width="250px" class="green3" | | ||
+ | <!-- PEOPLE HEADER with edit link--> | ||
+ | <h3><html> | ||
+ | <img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People"> | ||
+ | </html>People</h3> | ||
+ | <hr/> | ||
+ | <!-- END PEOPLE HEADER with edit link--> | ||
+ | The MIT iGEM team consists of six undergraduate students working full-time during summer 2008 on engineering a biological system. In addition, we have a number of graduate student and faculty advisers. | ||
+ | |||
+ | '''[[Picture of MIT iGEM 2008 (coming soon!)]]''' | ||
+ | |||
+ | ===Students=== | ||
+ | *[[User:Prarthna_Desai|Prarthna Desai]] | ||
+ | *[[User:Derek_Ju|Derek Ju]] | ||
+ | *[[User:John_Kucharczyk|John Kucharczyk]] | ||
+ | *[[User:Asad_Moten|Asad Moten]] | ||
+ | *[[User:Sara_Mouradian|Sara Mouradian]] | ||
+ | *[[User:Allin_Resposo|Allin Resposo]] | ||
+ | *[[User:Andrew_Ang|Andrew Ang]] | ||
+ | |||
+ | ===Grad Advisors=== | ||
+ | *[[User:Barbero|Robbie Barbero]] | ||
+ | *[[User:Scottmc|Scott Carlson]] | ||
+ | *[[User:Cookb|Brian Cook]] | ||
+ | *[[User:Rachel_A._Hillmer|Rachel Hillmer]] | ||
+ | *[[User:Lav_R._Varshney|Lav Varshney]] | ||
+ | *[[User:Lventouras|Laure-Anne Ventouras]] | ||
+ | *[[User:Chia-Yung_Wu|Chia-Yung Wu]] | ||
+ | *[[User:Vikram Yadav|Vikramaditya Yadav]] | ||
+ | *[[User:Fmoser|Felix Moser]] | ||
+ | *[[User:Jyoti_Goda|Jyoti Goda]] | ||
+ | *[[User:Woo Chung|Woo Chung]] | ||
+ | |||
+ | ==Faculty Advisors== | ||
+ | *[[Tom Knight]] | ||
+ | *[[Drew Endy]] | ||
+ | |||
+ | Email grads: '''grads [AT] igem.mit.edu''' | ||
+ | |||
+ | Email undergrads: '''team [AT] igem.mit.edu''' | ||
+ | |||
+ | alternative address: '''igem2008-all [AT] mit.edu''' | ||
+ | |||
+ | |} | ||
+ | </div> | ||
+ | __NOEDITSECTION__ | ||
+ | __NOTOC__ | ||
+ | |||
|[[Image:Teambiogurt.jpg|200px|right|frame]] | |[[Image:Teambiogurt.jpg|200px|right|frame]] | ||
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Revision as of 14:52, 24 June 2008
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* Our goal is to engineer a common yogurt bacteria, Lactobacillus bulgaricus, so that it will express the 20aa peptide p1025. A clinical study (Kelly CG et al.; Nature Biotechnol. 1999) reports that p1025 is good for your teeth. p1025 reduces oral colonization of Streptococcus mutans, a tooth-decaying bacterium. * o Stage 1: Construction of p1025 fusion peptide and expression of gene in E. coli. This is an intermediate step to evaluate gene function and protein secretion/efficacy. o Stage 2: Binding Assay - see if the p1025 produced by E.coli inhibits binding of S. mutants to hydroxyapatite (HA) beads. o Stage 3: Expression of p1025 in Lactobacillus. o Stage 4: Make yogurt with modified Lactobacillus and test for inhibition of S. mutants binding.
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Team Example 2 |
Home | The Team | The Project | Parts Submitted to the Registry | Modeling | Notebook |
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(Or you can choose different headings. But you must have a team page, a project page, and a notebook page.)