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Team:PennState
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| - | <td valign="top"><span style="font-size: | + | <td valign="top"><span style="font-size: 16pt">PENN STATE iGEM 2008</span> |
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<p>Welcome to the Penn State iGEM 2008 team website. We have been working hard at a few different projects for this year's competition. Starting this summer we began working trying to create different types of biosensors that use human nuclear hormone receptors to recognize potentially harmful ligands. We also have been finishing up one of last year's projects which is amied at more reaching efficent bioproduction by altering how <em>E. Coli</em> selects between utilizing 5 and 6 carbon sugars. Please explore our website to find out more about us and our projects!</p> | <p>Welcome to the Penn State iGEM 2008 team website. We have been working hard at a few different projects for this year's competition. Starting this summer we began working trying to create different types of biosensors that use human nuclear hormone receptors to recognize potentially harmful ligands. We also have been finishing up one of last year's projects which is amied at more reaching efficent bioproduction by altering how <em>E. Coli</em> selects between utilizing 5 and 6 carbon sugars. Please explore our website to find out more about us and our projects!</p> | ||
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| - | <td valign="top"><td style="padding-top:30px; padding-right:30px" valign="top" width="90%"><span style="font-size: | + | <td valign="top"><td style="padding-top:30px; padding-right:30px" valign="top" width="90%"><span style="font-size:14pt">Hormone Prescreening <em>E. coli</em></span> |
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<p>Our project aims to construct a bio sensor which will ultimately serve as a pre screening tool to detect the presence of phthalates in water sample. Recently phthalates have been shown to cause negative health effect in humans; some phthalates are even though to be carcinogenic. Analytical detection methods for these compounds are compound specific as well as very costly. Having a simple, and cheep tool to screen for phthalates as a general class of compounds would eliminate some of the cost and time involved in current detection methods.</p> | <p>Our project aims to construct a bio sensor which will ultimately serve as a pre screening tool to detect the presence of phthalates in water sample. Recently phthalates have been shown to cause negative health effect in humans; some phthalates are even though to be carcinogenic. Analytical detection methods for these compounds are compound specific as well as very costly. Having a simple, and cheep tool to screen for phthalates as a general class of compounds would eliminate some of the cost and time involved in current detection methods.</p> | ||
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| - | <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: | + | <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: 14pt">Smart Fold Reporter</span> |
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| - | <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: | + | <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: 14pt">Diauxie Elimination: <em>Two</em> spoons full of sugar.</span> |
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<p><img src="picture here" alt="[img]" style="float:left; margin:5px;"/>Cellulosic biomass is an aboundant and inexpensive energy source, coming from plant waste and the like: ideal for Ethanol production through fermentation. However, biomass contains glucose and xylose sugars in relatively equal ratios, while <em>e. coli</em> preferentially metabolizes glucose before any other sugar. In this project we attempt to eliminate this phenomenon, called <em>diauxie</em>, and get our cells to utilize both sugars at the same time. Solving this problem will lead to more efficent use of cellulosic biomass including moving towards the future of bioproduction: continous processes.</p> | <p><img src="picture here" alt="[img]" style="float:left; margin:5px;"/>Cellulosic biomass is an aboundant and inexpensive energy source, coming from plant waste and the like: ideal for Ethanol production through fermentation. However, biomass contains glucose and xylose sugars in relatively equal ratios, while <em>e. coli</em> preferentially metabolizes glucose before any other sugar. In this project we attempt to eliminate this phenomenon, called <em>diauxie</em>, and get our cells to utilize both sugars at the same time. Solving this problem will lead to more efficent use of cellulosic biomass including moving towards the future of bioproduction: continous processes.</p> | ||
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| - | <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: | + | <td style="padding-top:30px; padding-right:30px" valign="top" width="45%"><span style="font-size: 14pt">Drew Endy On Synthetic Biology</span> |
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| - | <h4 style="font-size: | + | <h4 style="font-size: 14pt;">Sponsors for our team! Thanks so much!</h4> |
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<img src="http://ntp.neuroscience.wisc.edu/gwis/gifs/Invitrogen.jpg" alt="invitrogen" style="float:left; clear: left; margin-right: 4%; margin-top: 40px; width: 48%;"/> | <img src="http://ntp.neuroscience.wisc.edu/gwis/gifs/Invitrogen.jpg" alt="invitrogen" style="float:left; clear: left; margin-right: 4%; margin-top: 40px; width: 48%;"/> | ||
Revision as of 19:54, 24 June 2008
| Home | The Team | The Project | Parts | Modeling | Notebook |
Hormone Biosensors
Diauxie Elimination
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PENN STATE iGEM 2008
Welcome to the Penn State iGEM 2008 team website. We have been working hard at a few different projects for this year's competition. Starting this summer we began working trying to create different types of biosensors that use human nuclear hormone receptors to recognize potentially harmful ligands. We also have been finishing up one of last year's projects which is amied at more reaching efficent bioproduction by altering how E. Coli selects between utilizing 5 and 6 carbon sugars. Please explore our website to find out more about us and our projects! If there are any questions or comments about the information on this site please contact us at gjt5001@psu.edu.
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Sponsors for our team! Thanks so much!
