"
Team:Paris/Flagella
From 2008.igem.org
| Line 4: | Line 4: | ||
|style="background:#ffffff"| | |style="background:#ffffff"| | ||
The construction of ''E. coli'' flagellar system is organized into a complex hierarchy. The different parts of the flagella are successively assembled parts by parts. This architecture is also present in the network of genes that contributes to its set-up. | The construction of ''E. coli'' flagellar system is organized into a complex hierarchy. The different parts of the flagella are successively assembled parts by parts. This architecture is also present in the network of genes that contributes to its set-up. | ||
| + | A global transcription factor FlhDC activates the synthesis of the flagella. This class 1 gene encodes a protein that activates the expression of class 2 genes. Those genes lead to the construction of the basal body of the flagella and its hook. Then FliA, a protein coded by a class 2 gene activates, with FlhDC to the expression of class 3 genes (''Figure 1''). | ||
| + | ==Bibliography== | ||
| + | xv S Kalir et coll., “Ordering genes in a flagella pathway by analysis of expression kinetics from living | ||
| + | bacteria,” Science (New York, N.Y.) 292, no. 5524 (Juin 15, 2001): 2080-3, doi:11408658 | ||
| + | [http://www.ncbi.nlm.nih.gov/pubmed/15186773?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum| Kalir ''et al.'' (2004)] | ||
|} | |} | ||
Revision as of 02:01, 29 October 2008
|
The construction of E. coli flagellar system is organized into a complex hierarchy. The different parts of the flagella are successively assembled parts by parts. This architecture is also present in the network of genes that contributes to its set-up. A global transcription factor FlhDC activates the synthesis of the flagella. This class 1 gene encodes a protein that activates the expression of class 2 genes. Those genes lead to the construction of the basal body of the flagella and its hook. Then FliA, a protein coded by a class 2 gene activates, with FlhDC to the expression of class 3 genes (Figure 1). Bibliographyxv S Kalir et coll., “Ordering genes in a flagella pathway by analysis of expression kinetics from living bacteria,” Science (New York, N.Y.) 292, no. 5524 (Juin 15, 2001): 2080-3, doi:11408658 [http://www.ncbi.nlm.nih.gov/pubmed/15186773?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum| Kalir et al. (2004)] |
