Sequestillator Model 1: A simple model

Parameters:

• At= total amount of NifA
• tmax= maximal transcription rate
• tl=translation rate
• r = conversion rate from La to Lb
• any d= degradation rate of that species

This simple system assumes the total amount of NifA in the system is constant, and considers three variable: NifL mRNA (mL), NifL (La), and a simple covalent modification of NifL (Lb).

Table 1

We see that if we increase our search range for the dissociation constant to 0 to .1, then we get a substantially less Ninfa index, illustrating the importance of having a tight binding between NifA and NifL.

Table 2

We again see the necessity of a tight binding between NifA and NifL