Team:Groningen/Modeling

Modeling

To gain insight into the working of our designs we try to develop reliable and realistic models.

The ODE solvers incorporated in the SimBiology package, for Mathworks' Matlab, are employed to model the genetic design on the single-cell level, displaying the variations in concentration of all relevant substances over time.

To examine the workings of our designs on the multi-cell level we are developing a routine in Matlab which can predict the collective behaviour of the designed cells on a two-dimensional grid. Hopefully this will help us to gain more insight in the characteristics of AHL exchange between the cells.