Team:NTU-Singapore
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Team background
The NTU-Singapore iGEM08 team consists of six undergraduate students working full-time from May to July 2008 . In addition, we have a number of graduate students and faculty advisors.
Students
Faculty Advisors
Student HelperLu Chao (Year 4 Bio-Engineering Student)
| File:NTU logo ver2.jpg Our team logo File:NTU igem team members2.JPG Our team members (left to right): Yu Chin Chong, Wong Choon Kit, Ng Zhen Fu, Nguyen Xuan Hung, Lim Min-Lin, Darius Aw Kang Lie, |
Project introduction
Our group has decided to engineer E.coli as a carrier for colicin E7 to deal with the pathogenic strain of Ecoli known as Escherichia coli O157:H7. Escherichia coli O157:H7 is an enterohemorrhagic strain that can cause bloody diarrhea and kidney failure. Current methods of cure for the infection include blood transfusion and dialysis. Currently no antibiotic is able to kill it.
Our approach is to use Colicin E7 to kill this harmful strain of bacteria. We intend to use our very own genetically engineered E.coli as the carrier of the colicin. We also wish for our bacteria to able to detect the presence of blood and the bacteria before it releases the colicins to eradicate the pathogen.
Our aim would be to control the level of colicin production in our bacteria. Our engineered bacteria should also be able to be accurate in its detection.
For any comments or enquiries, contact us at ntu.igem@gmail.com
Upcoming important events
1 July | Team project descriptions due (Early summer teams) |
Team registration fee due | |
1 September | Final team rosters due |
1 October | Jamboree attendance fees due; notice and description of any use of non-standard parts or devices schemes due |
15 October | Project Summary forms due (to allow for organization of judging) |
29 October | Project and part documentation due |
29 October | BioBrick Part DNA received by the Registry |
8-9 November | iGEM Competition Jamboree, MIT, USA |