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Josh Michener

Education

• 2nd year Bioengineering grad student at Caltech
• S.B. 2006, Chemical Engineering and Biology at MIT

Lab history

• Grad student in the Smolke Lab at Caltech.
• Rotated in the Smolke, Arnold, and Elowitz labs at Caltech
• UROP in the Endy Lab at MIT, January 2005 - January 2006.

Contact Info

Josh Michener
1200 E. California Blvd.
MC 210-41
Pasadena, CA, 91125

Research

My research focuses on applying RNA switches, developed elsewhere in the lab, to provide dynamic control of enzymatic pathways. Specifically, I am using those switches to construct feedback control systems, with the goal of producing a predictable output despite variations in reaction conditions. These control systems can then be used in metabolic engineering to change both the transient and equilibrium responses of a pathway.

Past Projects

• Development of an in vivo screen for synthetic riboswitches.
• Design and construction of a screening plasmid measure the PoPS transfer curve of a BioBricks device.