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From 2008.igem.org

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We are the inaugural iGEM team here at the University of Illinois. We are very excited to be participating and look forward to a summer full of fun, learning, and hopefully a successful project.

Contents 1 Overall project 2 Subprojects 2.1 Antibody GPCR Fusion 2.2 Antibody Receptor Tyrosine Kinase Fusion 2.3 Bimolecular Fluoresence 3 Results

Overall project

For our project we intend to create a yeast-based biosensor capable of detecting and signalling the presense of a pathogen. We intend to use directed evolution to develop a cell surface receptor capable of binding the pathogen. This receptor will then initiate a signaling cascade which will induce a change in the yeast, a color change for example. This project is important because there is a demonstrated need for cheap and effective monitoring of water-borne pathogens in the third world where traditional detection methods are not feasible.

Subprojects

To improve our odds of achieving our project we have decided to modulate our team into 3 disparate groups, each pursuing variant methods to accomplish the above goal, that is, cheap detection of water-bourne pathogens. The three methods and teams are detailed below.

If you were not present at the June 10th meeting, pick a group and contact the members.

Antibody GPCR Fusion

Antibody Receptor Tyrosine Kinase Fusion

Bimolecular Fluoresence

Results

Home	The Team	Notebook	Research Articles	Protocols	The Project	Pictures	Parts Submitted to the Registry

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