Genetic toggle switch to implement rewritable function

We think two type models - genetic circuit model and mathematical model.

Genetic circuit model

fig5-1:genetic circuit model

1. Writable function

・ Plac is induced under 30MPa pressure(PL is weakly induced)

・ Express CI and GFP

・ CI represses PL and causes low LacI concentration

・ Express increasingly CI and GFP ⇒ Bright!!

2. Erasable function

・PL is induced by heat

・Express LacI and LacI represses Plac

・Therefore, GFP expression decreases