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Team:Chiba/Sender
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Each species has their own LuxI-type proteins,which synthesize their specific autoinducers,AHLs.AHLs produced by different LuxI-type proteins differ only in the length of the acyl-chain moiety and substitution at position C-3.LuxR,which is original for Vibrio fischeri,is activated by its cognate autoinducer,3OC6HSL.However,LuxR is also activated by non-endogenous molecules,C4HSL,C6HSL,and 3OC12HSL.Activation by non-endogenous molecules requires a higher signal concentration(2).This results in slower activation of receivers,when AHL concentration is increasing. | Each species has their own LuxI-type proteins,which synthesize their specific autoinducers,AHLs.AHLs produced by different LuxI-type proteins differ only in the length of the acyl-chain moiety and substitution at position C-3.LuxR,which is original for Vibrio fischeri,is activated by its cognate autoinducer,3OC6HSL.However,LuxR is also activated by non-endogenous molecules,C4HSL,C6HSL,and 3OC12HSL.Activation by non-endogenous molecules requires a higher signal concentration(2).This results in slower activation of receivers,when AHL concentration is increasing. | ||
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[[Image:AHL variety chiba.gif|frame|'''Fig.4''' AHL varieties]] | [[Image:AHL variety chiba.gif|frame|'''Fig.4''' AHL varieties]] | ||
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| + | AHLsおよびその合成酵素 | ||
| + | <table width="500" border="1" cellpadding="0" cellspacing="0" bordercolor="#000000" center> | ||
| + | <tr> | ||
| + | <td width="200">Strain</td> | ||
| + | <td width="200">AHL</td> | ||
| + | <td width="150">LuxI-type protein<td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td>P.aeruginosa</td> | ||
| + | <td>C4HSL, C6HSL</td> | ||
| + | <td>RhlI</td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td>V. fisheri</td> | ||
| + | <td>3OC6HSL</td> | ||
| + | <td>LuxI</td> | ||
| + | </tr> | ||
| + | <tr> | ||
| + | <td>P.aeruginosa</td> | ||
| + | <td>3OC12HSL</td> | ||
| + | <td>LasI</td> | ||
| + | </tr> | ||
| + | </table> | ||
<br clear=all> | <br clear=all> | ||
Latest revision as of 18:32, 26 October 2008
| Home | The Team | The Project | Parts Submitted to the Registry | Reference | Notebook | Acknowledgements |
|---|
Signal molecule sender
Design
Each species has their own LuxI-type proteins,which synthesize their specific autoinducers,AHLs.AHLs produced by different LuxI-type proteins differ only in the length of the acyl-chain moiety and substitution at position C-3.LuxR,which is original for Vibrio fischeri,is activated by its cognate autoinducer,3OC6HSL.However,LuxR is also activated by non-endogenous molecules,C4HSL,C6HSL,and 3OC12HSL.Activation by non-endogenous molecules requires a higher signal concentration(2).This results in slower activation of receivers,when AHL concentration is increasing.
Fig.4 AHL varieties
AHLsおよびその合成酵素
| Strain | AHL | LuxI-type protein | |
| P.aeruginosa | C4HSL, C6HSL | RhlI | |
| V. fisheri | 3OC6HSL | LuxI | |
| P.aeruginosa | 3OC12HSL | LasI |
Experiment
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