Team:Imperial College/Genetic Circuit Details

From 2008.igem.org

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No intermediary P-IPTG-LacI complex is formed.
No intermediary P-IPTG-LacI complex is formed.
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We assumed 2 LacI molecules bind to the promoter.
We assumed 2 LacI molecules bind to the promoter.

Revision as of 16:50, 28 October 2008


Simple Model (1)


Equilibria

Equations


More Sophisticated Model(2)


Equilibria

Assumptions:

No intermediary P-IPTG-LacI complex is formed.

We assumed 2 LacI molecules bind to the promoter.

Equations

Qualitative effect of parameters on behaviour


References
  1. Kuhlman T, Zhang Z, Saier MH Jr, & Hwa T (2007) Combinatorial transcriptional control of the lactose operon of Escherichia coli. - PNAS 104 (14) 6043-6048
  2. Alon, U (2006) An Introduction to Systems Biology: Design Principles of Biological Circuits - Chapman & Hall/Crc Mathematical and Computational Biology