Team:Paris/Network analysis and design/System improvements

From 2008.igem.org

(Difference between revisions)
(→System Improvements)
(→System Improvements)
Line 1: Line 1:
 +
<center>
 +
{|
 +
|- style="background: #649CD7;"
 +
! colspan="4" style="background: #649CD7;" | System Improvements
 +
|- style="background: #649CD7; text-align: center;"
 +
| Name
 +
| Description
 +
| Evaluation
 +
| Links
 +
|- style="background: #dddddd;" 
 +
| style="background: #D4E2EF;"|Core system
 +
| Figure core system
 +
| Zero
 +
| Liks core system
 +
|- style="background: #dddddd;"
 +
| style="background: #D4E2EF;" |Modular system
 +
| Figure modular system
 +
| **
 +
| Links Garcia-Ojalvo
 +
|- style="background: #dddddd;"
 +
| style="background: #D4E2EF;" |Resulting system
 +
| Figure resulting system
 +
| ***
 +
| Links resulting
 +
|}</center>
 +
 +
<!--
== System Improvements ==
== System Improvements ==
 +
-->
Core system does not oscillate. How can we enhance it?
Core system does not oscillate. How can we enhance it?

Revision as of 18:53, 25 October 2008

System Improvements
Name Description Evaluation Links
Core system Figure core system Zero Liks core system
Modular system Figure modular system ** Links Garcia-Ojalvo
Resulting system Figure resulting system *** Links resulting


Core system does not oscillate. How can we enhance it?

We need a 'delay' so we can: 1 add more genes to the circuit 2 use quorum sensing (qs)

we chose quorum sensing that can allowed both 'delay' and population synchonization. two ways to add it: S4 and S2.

We first analyse S4 due to modularity.

Inspired from Garcia-Ojalvo: oscillating repressilator + oscillating qs module = synchronized oscillations

we tried s4:

damped oscillating core system + oscillating qs module = damped oscillations.

We continue with S2:

S0 module in S4 gived us insides in parameters analysis for S2.

given analysis results we keep S2.

Retrieved from "http://2008.igem.org/Team:Paris/Network_analysis_and_design/System_improvements"