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Team:Purdue/Modeling
From 2008.igem.org
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| - | #2005. Response times and mechanisms of SOS induction by attaching promoters to GFP: [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1151601]. Potential Validation Data Set. Model should predict similar dynamics. | + | #2005. Response times and mechanisms of SOS induction by attaching promoters to GFP: "Precise Temporal Modulation in the Response of the SOS DNA Repair Network in Individual Bacteria" [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1151601]. Potential Validation Data Set. Model should predict similar dynamics. |
<!--- The Mission, Experiments ---> | <!--- The Mission, Experiments ---> | ||
Revision as of 03:15, 20 June 2008
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Modeling Objectives
- Develop a mechanistics ODE model of the population to predict gene expression dynamics
- Question? .... Will the color production be fast enough to be useful to the user? Or will it be too late?
- What is the relationship between UV exposure and reporter gene expression?
- Can we construct a useful calibration curve of color as a function of UV?
Modeling References
- 2005. Response times and mechanisms of SOS induction by attaching promoters to GFP: "Precise Temporal Modulation in the Response of the SOS DNA Repair Network in Individual Bacteria" [1]. Potential Validation Data Set. Model should predict similar dynamics.
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