Team:Slovenia/Conclusions
From 2008.igem.org
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<li>Analyze different combinations of antigen-TLRs to obtain optimal immune stimulation (TLR synergy)</li> | <li>Analyze different combinations of antigen-TLRs to obtain optimal immune stimulation (TLR synergy)</li> | ||
<li>Repeat all experiments with many controls, in comparison to currently used adjuvants etc</li> | <li>Repeat all experiments with many controls, in comparison to currently used adjuvants etc</li> | ||
+ | <li>... ... (ars longa, vita brevis)</li> | ||
</ul><br /><br /> | </ul><br /><br /> | ||
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<li>The approach with chimeric flagellins could be used against other flagellated bacteria whose flagellin does not activate innate system (<i>Bartonella, Campylobacter, Borellia</i>...)</li> | <li>The approach with chimeric flagellins could be used against other flagellated bacteria whose flagellin does not activate innate system (<i>Bartonella, Campylobacter, Borellia</i>...)</li> | ||
<li>Could vaccines based on antigen-TLR fusions be used as tumor vaccines as well?</li> | <li>Could vaccines based on antigen-TLR fusions be used as tumor vaccines as well?</li> | ||
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<li>Two chimeric recombinant protein vaccines showed intense IgG antibody response in mice and immunized sera also reacted with heat-killed <i>H. pylori</i> antigens implying that they recognize epitopes of <i>H. pylori</i>.</li> | <li>Two chimeric recombinant protein vaccines showed intense IgG antibody response in mice and immunized sera also reacted with heat-killed <i>H. pylori</i> antigens implying that they recognize epitopes of <i>H. pylori</i>.</li> | ||
</ul> | </ul> |
Revision as of 00:39, 30 October 2008
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Achievements
What remains to be done ?
Prospects
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