Team:UC Berkeley Tools

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With >700 available parts and >2000 defined parts in the [http://partsregistry.org/Main_Page MIT Registry of Standard Biological Parts], and doubtless more parts local to the lab, synthetic biologists are now faced with the challenge of organizing, sorting, and editing these parts from an ever-growing collection of DNA. Computational tools are becoming increasingly needed to assist biologists to do the job, and it is no secret that many tools are indeed wheeling out into the community to help serve these needs.
With >700 available parts and >2000 defined parts in the [http://partsregistry.org/Main_Page MIT Registry of Standard Biological Parts], and doubtless more parts local to the lab, synthetic biologists are now faced with the challenge of organizing, sorting, and editing these parts from an ever-growing collection of DNA. Computational tools are becoming increasingly needed to assist biologists to do the job, and it is no secret that many tools are indeed wheeling out into the community to help serve these needs.
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Clotho is a toolset designed in a platform-based-design paradigm to consolidate all these tools into one working, integrated toolbox. Clotho is based on a core-and-hub system which manages multiple connections, each connection serving an independent purpose in an almost self-sufficient manner. Examples of connections include sequence viewers/editors, parts database managers, sequence alignment GUIs, and much more. Computer-savvy biologists can create new connections which will then be integrated into Clotho. In this tool-consolidation and customization it is hoped that, in the future, biologists need not look further for a program that provides the answer to their needs.
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Clotho is a toolset designed in a platform-based-design paradigm to consolidate all these tools into one working, integrated toolbox. Clotho is based on a core-and-hub system which manages multiple connections, each connection performing tasks in some self-sufficient manner while connected to all other connections via the core. Examples of connections include sequence viewers/editors, parts database managers, sequence alignment GUIs, and much more. Computer-savvy biologists can create new connections which will then be integrated into Clotho. In this tool-consolidation and customization it is hoped that, in the future, biologists need not look further for a program that provides the answer to their needs.
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Revision as of 23:10, 17 October 2008

Clotho Title small.png
[http://biocad-server.eecs.berkeley.edu/wiki/index.php/Clotho_Development#Downloads_and_Information The Alpha release is here.]


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With >700 available parts and >2000 defined parts in the [http://partsregistry.org/Main_Page MIT Registry of Standard Biological Parts], and doubtless more parts local to the lab, synthetic biologists are now faced with the challenge of organizing, sorting, and editing these parts from an ever-growing collection of DNA. Computational tools are becoming increasingly needed to assist biologists to do the job, and it is no secret that many tools are indeed wheeling out into the community to help serve these needs.

Clotho is a toolset designed in a platform-based-design paradigm to consolidate all these tools into one working, integrated toolbox. Clotho is based on a core-and-hub system which manages multiple connections, each connection performing tasks in some self-sufficient manner while connected to all other connections via the core. Examples of connections include sequence viewers/editors, parts database managers, sequence alignment GUIs, and much more. Computer-savvy biologists can create new connections which will then be integrated into Clotho. In this tool-consolidation and customization it is hoped that, in the future, biologists need not look further for a program that provides the answer to their needs.


Clotho Overview

Overview of the Clotho Design Environment

The Clotho design environment is



Clotho Database Interaction Models



Contact Us

For general information or to contribute: clothodevelopment AT googlegroups DOT com

For emails regarding any bugs: clothobugs AT googlegroups DOT com

For emails regarding any desired features: clothofeatures AT googlegroups DOT com